Emodepside — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Emodepside is a cyclo-octadepsipeptide anthelmintic (tapeworm, cats).
Total reports
Emodepside: 4964
Reports by species (top entries)
- Cat 4612
- Human 73
- Dog 36
- Rabbit 1
- Whale 1
Top reported reactions (VEDDRA terms, top entries)
- Application site alopecia 1121
- Hypersalivation 827
- Lethargy (see also Central nervous system depression in 'Neurological') 649
- Vomiting 462
- Ataxia 384
- Lack of efficacy (endoparasite) - tapeworm 376
- Behavioural disorder NOS 337
- Anorexia 299
- Application site erythema 266
- Application site pruritus 264
"Lack of efficacy" terms denote product-performance reports, not adverse reactions.
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b8.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).