Difloxacin Hydrochloride — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Difloxacin Hydrochloride is a active ingredient.
Total reports
Difloxacin Hydrochloride: 91
Reports by species (top entries)
- Dog 73
- Cat 3
- Human 1
Top reported reactions (VEDDRA terms, top entries)
- Anorexia 13
- Depression 12
- Vomiting 10
- Convulsion 7
- Death 7
- Death by euthanasia 7
- Lack of efficacy (bacteria) - NOS 7
- Elevated serum alkaline phosphatase (SAP) 6
- Fever 5
- Tablets, Abnormal 5
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b21.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).