Cyproheptadine — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Cyproheptadine is a active ingredient.
Total reports
Cyproheptadine: 43
Reports by species (top entries)
- Cat 34
- Dog 7
- Horse 1
- Human 1
Top reported reactions (VEDDRA terms, top entries)
- Weight loss 12
- Lack of efficacy - NOS 7
- Anorexia 6
- Ataxia 6
- Vomiting 6
- Behavioural disorder NOS 5
- Death 5
- Decreased appetite 5
- Diarrhoea 5
- Lethargy (see also Central nervous system depression in Neurological) 5
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b25.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).