Cyphenothrin — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Cyphenothrin is a active ingredient.
Total reports
Cyphenothrin: 110
Reports by species (top entries)
- Dog 110
Top reported reactions (VEDDRA terms, top entries)
- Lack of efficacy (ectoparasite) - flea 18
- Vomiting 12
- Lack of efficacy (flea) 10
- Lethargy (see also Central nervous system depression in 'Neurological') 9
- Itching 7
- Restlessness 7
- Agitation 6
- INEFFECTIVE, HOOKS 6
- Other abnormal test result NOS 6
- Seizure NOS 6
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b20.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).