Codeine — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Codeine is a active ingredient.
Total reports
Codeine: 70
Reports by species (top entries)
- Dog 68
- Human 2
Top reported reactions (VEDDRA terms, top entries)
- Death by euthanasia 13
- Vomiting 13
- Decreased appetite 10
- Diarrhoea 10
- Elevated alanine aminotransferase (ALT) 9
- Abnormal ultrasound finding 8
- Pain NOS 8
- Panting 8
- Death 7
- Inappetence 7
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b23.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).