Ciprofloxacin — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Ciprofloxacin is a veterinary active ingredient.
Total reports
Ciprofloxacin: 297
Reports by species (top entries)
- Dog 273
- Cat 19
- Human 2
- Parrot 2
- Horse 1
Top reported reactions (VEDDRA terms, top entries)
- Lethargy (see also Central nervous system depression in 'Neurological') 59
- Vomiting 51
- Other abnormal test result NOS 46
- Emesis 34
- Death by euthanasia 33
- Diarrhoea 33
- Elevated alanine aminotransferase (ALT) 32
- Anorexia 28
- Elevated serum alkaline phosphatase (SAP) 26
- Lack of efficacy - NOS 21
"Lack of efficacy" terms denote product-performance reports, not adverse reactions.
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b5.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).