Cimetidine — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Cimetidine is a active ingredient.
Total reports
Cimetidine: 52
Reports by species (top entries)
- Dog 46
- Cat 2
- Horse 2
- Human 1
- Other Canids 1
Top reported reactions (VEDDRA terms, top entries)
- Vomiting 18
- Diarrhoea 11
- Anorexia 8
- Lethargy (see also Central nervous system depression in 'Neurological') 8
- Elevated serum alkaline phosphatase (SAP) 7
- Elevated alanine aminotransferase (ALT) 6
- Lack of efficacy - NOS 6
- Death by euthanasia 5
- Elevated blood urea nitrogen (BUN) 5
- Elevated creatinine 5
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b24.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).