chlorphenamine — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-08-16. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. "chlorphenamine" is a name as filed in the drug active-ingredient field of these reports (may be a generic ingredient or a product/brand name as reported).
Total reports
chlorphenamine: 88
Reports by species (top entries)
- Dog 76
- Cat 12
Top reported reactions (VEDDRA terms, top entries)
- Emesis 33
- Vomiting 20
- Lack of efficacy - NOS 10
- Lethargy (see also Central nervous system depression in 'Neurological') 10
- Behavioural disorder NOS 6
- Elevated alanine aminotransferase (ALT) 4
- Bloody diarrhoea 3
- Cataract 3
- Death 3
- Decreased appetite 3
"Lack of efficacy" terms denote product-performance reports, not adverse reactions.
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-08-16_b1.json (openFDA animalandveterinary/event.json, pulled 2026-08-16).