Chlorhexidine Gluconate — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Chlorhexidine Gluconate is a active ingredient.
Total reports
Chlorhexidine Gluconate: 478
Reports by species (top entries)
- Dog 399
- Cat 53
- Human 26
Top reported reactions (VEDDRA terms, top entries)
- Application site erythema 90
- Application site pruritus 29
- Pruritus 26
- Application site hair coat discolouration 25
- Lethargy (see also Central nervous system depression in 'Neurological') 25
- Application site irritation 24
- Application site reddening 20
- Vomiting 20
- Erythema (for urticaria see Immune SOC) 17
- Anorexia 15
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b13.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).