Chlorambucil — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Chlorambucil is a veterinary active ingredient.
Total reports
Chlorambucil: 106
Reports by species (top entries)
- Cat 72
- Dog 34
Top reported reactions (VEDDRA terms, top entries)
- Death by euthanasia 17
- Vomiting 14
- Diarrhoea 11
- Lack of efficacy - NOS 11
- Other abnormal test result NOS 11
- Anorexia 10
- Weight loss 10
- Death 8
- Lethargy (see also Central nervous system depression in 'Neurological') 8
- Behavioural disorder NOS 6
"Lack of efficacy" terms denote product-performance reports, not adverse reactions.
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b6.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).