Amlodipine — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Amlodipine is a veterinary active ingredient.
Total reports
Amlodipine: 769
Reports by species (top entries)
- Cat 378
- Dog 354
- Human 36
Top reported reactions (VEDDRA terms, top entries)
- Vomiting 112
- Diarrhoea 96
- Death by euthanasia 82
- Weight loss 80
- Decreased appetite 69
- Elevated blood urea nitrogen (BUN) 69
- Lethargy (see also Central nervous system depression in 'Neurological') 69
- Lethargy (see also Central nervous system depression in Neurological) 65
- Anorexia 64
- Lack of efficacy - NOS 62
"Lack of efficacy" terms denote product-performance reports, not adverse reactions.
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22_b6.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).