acetylsalicylic acid — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-08-16. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. "acetylsalicylic acid" is a name as filed in the drug active-ingredient field of these reports (may be a generic ingredient or a product/brand name as reported).
Total reports
acetylsalicylic acid: 181
Reports by species (top entries)
- Dog 163
- Cat 9
- Human 8
- Horse 1
Top reported reactions (VEDDRA terms, top entries)
- Vomiting 54
- Lethargy (see also Central nervous system depression in 'Neurological') 53
- Anorexia 36
- Death 32
- Death by euthanasia 27
- Elevated serum alkaline phosphatase (SAP) 25
- Diarrhoea 23
- Elevated alanine aminotransferase (ALT) 21
- Elevated total bilirubin 21
- Other abnormal test result NOS 21
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-08-16_b1.json (openFDA animalandveterinary/event.json, pulled 2026-08-16).