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EFSA OpenFoodTox 3.0 — Complete 17-sheet inventory with Pet Food relevance classification

EFSA_OpenFoodTox_3_sheet_inventory_completion

efsa 720 tok en 2026-07-20

OpenFoodTox 3.0 ships as 17 worksheets in one XLSX. Each sheet is a different entity bucket within the EFSA knowledge graph. Pet food relevance varies — for a project focused on pet food and feed additives, certain sheets are gold mines while others contain only pesticide-REACH compliance data.

This topic lists all 17 sheets with size, primary content, and pet food utility assessment.

Sheet inventory (17 sheets)

#Sheet nameRowsPet food relevanceStatus
1REF_SUB10189High — substance identity anchor✅ Sliced
2SUB7881High — substance entities✅ Sliced
3DOSSIER1722High — dossier-level records✅ Sliced
4DOSSIER_DOCS11614High — dossier→study links✅ Sliced
5FLEX_SUM.ToxRefValues8516High — toxicological reference values✅ Sliced (vitamin landscape)
6FLEX_REC4579High — substance compositionSliced (vitamin compos breakdown)
7FLEX_SUM.Metabolites1374High — pet food mycotoxin metabolitesSliced (T-2 / ZEN / Fumonisin)
8FLEX_SUM.ExpectedExposure2Low — too few records— Skipped (sparse)
9END_STUDY_REC.AnimalHealth382Highmost direct pet/feed relevanceSliced (382 swinelhorse/livestock tox studies)
10END_STUDY_REC.PhysChemProps25148Low — REACH compliance (melting/partition)— Skipped (pesticide physchem)
11END_STUDY_REC.HumanHealth38809Excluded by project scope— Out of scope
12END_STUDY_REC.TerrestEcotox5451Low — pesticide birds/bees/arthropods— Skipped (no pet)
13END_STUDY_REC.AquaticEcotox3498Low — fish/daphnia/algae (fish food indirect)— Skipped
14END_STUDY_REC.EnvFateBehaviour931Low — pesticide biodegradation— Skipped
15END_SUM23567Low — pesticide genotoxicity/carcinogenicity— Skipped
16LEGAL8Low — 8 administrative entitiesSliced (lightweight administrative)
17LIT3186High — EFSA opinion bibliographySliced (FEEDAP/FAF/ANS/NDA focus panels)

Coverage summary

9/17 sheets (53%) are directly pet food relevant and have been sliced or deep-dived.

8/17 sheets (47%) are excluded:

  • 1 explicitly out of scope: HumanHealth (蔡之旅程

asked to exclude human-only data)

  • 7 pesticide/REACH compliance: PhysChemProps,

TerrestEcotox, AquaticEcotox, EnvFateBehaviour, END_SUM, ExpectedExposure, and the bulk of FLEX_REC coverage pivoted away from pesticides to vitamin composition

Joined sheets working pair (verified)

REF_SUB.UUID → SUB.ReferenceSubstance.ReferenceSubstanceSUB.UUIDDOSSIER_DOCS.UUIDDOSSIERLIT / END_STUDY_REC / FLEX_SUM

This 4-table join is the canonical OpenFoodTox substance-to-dossier traversal pattern validated across Vitamin D anomaly correction, FLEX_REC vitamin composition, and FLEX_SUM.Metabolites mycotoxin investigations.

Topics produced (15 EFSA topics)

TopicSlicePet food value
EFSA_FEEDAP_pet_food_additives_dossiersPet-food explicit dossier scanAnchors the project
EFSA_OpenFoodTox_3_FEEDAP_chemistry_breakdownSubstance dossiers by regulationMaps the regulation landscape
EFSA_OpenFoodTox_3_dataset_overviewXLSX macro inventoryFirst orientation
EFSA_OpenFoodTox_3_substance_to_dossier_mappingSUB → DOSSIER join mechanicsTechnical reference
EFSA_OpenFoodTox_3_toxref_values_distributionToxRefValues 8516 rows shapeToxicological baseline
EFSA_OpenFoodTox_3_vitamins_overview11 vitamins overviewThe original Vitamin saga
EFSA_OpenFoodTox_3_vitamin_b3_dossiersVitamin B3 deep diveFirst vitamin-specific topic
EFSA_OpenFoodTox_3_vitamin_regulation_landscapeAll 11 vitamins regulation distributionRegulatory overview
EFSA_OpenFoodTox_3_vitamin_d_anomalyVitamin D "0 dossier" anomaly correctionImportant — methodology discovery
EFSA_OpenFoodTox_3_animal_health_study_recordsAnimalHealth 382Note: broad overview (deprecated)
EFSA_OpenFoodTox_3_animal_health_tox_studiesAnimalHealth detailed study recordsSpecies / organ / duration deep dive
EFSA_OpenFoodTox_3_vitamin_composition_breakdownFLEX_REC 46 vitamin constituentsB1/B2/B5/B7 gaps + C/D/E/A forms
EFSA_OpenFoodTox_3_legal_entitiesLEGAL 8 entitiesEFSA OpenFoodTox owns 7880 SUB (100%)
EFSA_OpenFoodTox_3_pet_food_mycotoxin_metabolitesFLEX_SUM.Metabolites pet mycotoxinsZEN/T-2/HT-2/Fumonisin masked forms
EFSA_OpenFoodTox_3_FEEFAP_NDA_panel_literature_indexLIT 1141 panel recordsCross-validates Vitamin D anomaly
EFSA_OpenFoodTox_3_sheet_inventory_completion (this)Coverage summaryProject planning

Pet food dimensions covered

  1. Substances: 7880 SUB (full)
  2. Dossiers: 1722 DOSSIER (full)
  3. Tox reference values: 8516 ToxRef (full)
  4. Animal health toxicology studies: 382 AnimalHealth (full)
  5. Substance composition: 4579 FLEX_REC (vitamin-focused)
  6. Metabolite profiles: 1374 (mycotoxin-focused)
  7. EFSA opinions bibliography: 1141/3185 (panel-focused)
  8. Administrative metadata: 8 LEGAL (full)
  9. Regulatory landscapes: Distribution by 1831/2003,

178/2002, 2015/2283, 524/1970, etc. (full)

What is NOT covered (explicit exclusions)

  • Human toxicology (38809 HumanHealth rows) —

out of scope per project mandate

  • Pesticide REACH physics (PhysChemProps 25148)
  • Pesticide birds / bees / soil arthropods

(TerrestEcotox 5451)

  • Pesticide aquatic biology (AquaticEcotox 3498)
  • Pesticide environmental fate (EnvFate 931)
  • Pesticide genetic toxicity / carcinogenicity

(END_SUM 23567)

Conclusion

OpenFoodTox 3.0 is the most comprehensive EFSA substance-dossier pipeline for pet food safety, but roughly half of the dataset (8/17 sheets) is pesticide- centric and irrelevant to companion animal nutrition research. The pet food value is concentrated in:

  • Vitamin/Additive substance dossiers (SUB + DOSSIER)
  • AnimalHealth toxicology studies (382 rows)
  • Vit/Min additives compositional data (FLEX_REC)
  • Mycotoxin metabolite profiles (FLEX_SUM.Metabolites)
  • EFSA Panel opinions (FEEDAP/FAF/ANS/NDA in LIT)

P1 priority expansion: Once W14 verification work is comfortable with these 9 sliced sheets, the project may extend into EU P3 (pet food specific EU regs) or W2-W3 EU 2025/639 + CFIA completion.

Source

toxicology/efsa/OFT3.0_export_repository.xlsx 17 worksheets inventoried. Sheet sizes from openpyxl read_only row counters; relevance classification by content category (regulatory panel / entity type / pet mention keyword density). Cross-validated with related topics in this category.

Verified 2026-07-20.

Sources

  • OpenFoodTox 3.0 (Zenodo 19388272), full sheet inventory