ECFR pet food GRAS CFR582

21 CFR 582 lists substances Generally Recognized As Safe (GRAS) for use in animal feed — the parsed corpus holds 243 sections. Entries relevant to pet food include: 582.10 (spices and other natural seasonings and flavorings), 582.20 (essential oils, oleoresins, and natural extractives), 582.30/582.40/582.50 (related natural substances), 582.2729 (hydrated sodium calcium aluminosilicate, anti-caking), 582.3169 BHA and 582.3173 BHT (antioxidants), 582.3640 (potassium sorbate, preservative), 582.3890 and 582.5890 (tocopherols) with 582.5892 (a-tocopherol acetate), and 582.1666 / 582.4666 (propylene glycol, permitted in non-cat applications). Critically, propylene glycol is prohibited in or on cat food — that prohibition sits in 21 CFR 589.1001, not in part 582 — because it causes Heinz body formation in cats. (Earlier drafts of this topic cited nonexistent or misassigned sections: 582.100, 582.1041, 582.5062, 582.5275 and 582.5279 do not exist in the parsed part, and 582.3640 is potassium sorbate, not an anticaking agent or tocopherols.) GRAS use in pet food should be at the functional minimum level needed for the intended technical effect; where 21 CFR 573 (feed additives) also lists the same substance, the additive-specific listing governs conditions of use.