Cyclosporine — FDA Animal & Veterinary Adverse Event (ADE) Reports
Source: openFDA animalandveterinary/event.json, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Cyclosporine is a veterinary active ingredient.
Total reports
Cyclosporine: 21560
Reports by species (top entries)
- Dog 15012
- Cat 2987
- Human 78
- 2
- Other 2
Top reported reactions (VEDDRA terms, top entries)
- Vomiting 5175
- Diarrhoea 2864
- Anorexia 1468
- Depression 1354
- Pruritus 1160
- Emesis 1077
- Lethargy (see also Central nervous system depression in 'Neurological') 939
- Other abnormal test result NOS 935
- Weight loss 890
- Elevated serum alkaline phosphatase (SAP) 734
"Lack of efficacy" terms denote product-performance reports, not adverse reactions.
Source JSON: pdf-raw/ade/ade_active_ingredients_2026-07-22.json (openFDA animalandveterinary/event.json, pulled 2026-07-22).