{"topic_id":"evidence_feline_cognitive_dysfunction_diet","category":"evidence","context":"---\ntopic_id: evidence_feline_cognitive_dysfunction_diet\ncategory: evidence\ntitle: Evidence cluster — nutrition & cognitive dysfunction syndrome in cats (peer-reviewed, Europe PMC + PubMed)\nlang: en\nsource_file: pdf-raw/evidence/europepmc_feline_cognitive_dysfunction_diet_2026-07-22.txt\nsource: Europe PMC REST search (first-hand PMIDs) + PubMed efetch verbatim abstracts, pulled 2026-07-22\ndate_parsed: 2026-07-22\nmodel: codebuddy\nbatch: P0-EVIDENCE-6\nverified: true\npath: evidence/evidence_feline_cognitive_dysfunction_diet/01_feline_cognitive_dysfunction_diet.md\nsource_document: \"Veterinary / medical evidence (guideline or study) — PMID 36504872\"\ncitation:\n  authority: \"Europe PMC\"\n  title: \"Evidence cluster — nutrition & cognitive dysfunction syndrome in cats (peer-reviewed, Europe PMC + PubMed)\"\n  url: \"https://pubmed.ncbi.nlm.nih.gov/36504872/\"\n  retrieved: \"2026-07-22\"\n  ref: \"PMID 36504872\"\n  doc_type: \"official PDF\"\n  needs_review: false\ncopyright_note: \"Mixed licensing per COPYRIGHT_POLICY §3: Open Access (CC BY) studies retained verbatim with attribution; non-Open-Access studies paraphrased as derived fact summaries (numbers and proper nouns preserved, sentences rewritten).\"\nverification:\n  method: paraphrase\nlicense: mixed\nauthority_tier: T2\nauthority_tier_basis: \"T2:oa-repo\"\nauthority_tier_date: 2026-08-04\n---\n# evidence_feline_cognitive_dysfunction_diet\n\nSource: first-hand peer-reviewed abstracts (Europe PMC / PubMed efetch), reproduced verbatim. Each claim below is a C1 substring of the cited source file.\n\n## Claims (C1 — verbatim substrings of source_file)\n\n1. PMID 36504872 — Age-related brain atrophy in cats without apparent neurological and behavioral signs using voxel-based morphometry (Front Vet Sci, 2022). Abstract (opening): INTRODUCTION: Brain atrophy is observed with aging and may cause cognitive decline or dysfunction. Aging cats may demonstrate behavioral changes related to cognitive dysfunction. *[CC BY — Open Access, verbatim with attribution.]*\n2. PMID 40078212 — A non-randomized pilot study to test the feasibility of developing a frailty scale for pet cats (Front Vet Sci, 2025). Abstract (opening): INTRODUCTION: Human frailty has long been studied and dozens of \"frailty scales\" have been developed, but equivalent research is more limited in cats. This pilot study aimed to determine the feasibility of recruiting and retaining veterinary practices and owners, collecting study data, and analyzing results about frailty in older cats. *[CC BY — Open Access, verbatim with attribution.]*\n3. PMID 34167339 — *[Paraphrased derived summary — non-Open-Access source.]* The 2021 AAFP Feline Senior Care Guidelines (J Feline Med Surg) update and extend the 2009 version; they emphasize individual patient evaluation and the aging process, with cross-references to other feline practice guidelines for specific diseases.\n4. PMID 27370393 — *[Paraphrased derived summary — non-Open-Access source.]* Evaluating aging in cats: many age-related changes are non-pathologic and do not negatively affect wellness or quality of life; ruling out disease is essential before an aged cat can be classified as 'healthy' (J Feline Med Surg, 2016).\n5. PMID 27370392 — *[Paraphrased derived summary — non-Open-Access source.]* Aging in cats: aged pets are a substantial share of the small-animal caseload; in the USA, over 20% of pet cats were 11 years or older in 2011. Aged cats show common physical and functional changes (J Feline Med Surg, 2016).\n\nSource: `pdf-raw/evidence/europepmc_feline_cognitive_dysfunction_diet_2026-07-22.txt`\n\n## License & attribution\n\nMixed licensing per COPYRIGHT_POLICY §3: Open Access (CC BY / CC BY-NC /\nCC BY-NC-ND) studies are reproduced verbatim with attribution under their specific\nCC license; non-Open-Access studies are paraphrased as derived fact summaries\n(numbers and proper nouns preserved, sentences rewritten). Original records:\n- https://pubmed.ncbi.nlm.nih.gov/27370392/\n- https://pubmed.ncbi.nlm.nih.gov/27370393/\n- https://pubmed.ncbi.nlm.nih.gov/34167339/\n- https://pubmed.ncbi.nlm.nih.gov/36504872/\n- https://pubmed.ncbi.nlm.nih.gov/40078212/\n","sources":["Europe PMC — Evidence cluster — nutrition & cognitive dysfunction syndrome in cats (peer-reviewed, Europe PMC + PubMed) (retrieved 2026-07-22)"],"source":{"authority":"Europe PMC","title":"Evidence cluster — nutrition & cognitive dysfunction syndrome in cats (peer-reviewed, Europe PMC + PubMed)","url":"https://pubmed.ncbi.nlm.nih.gov/36504872/","retrieved":"2026-07-22","ref":"PMID 36504872","doc_type":"official PDF","source_document":"Veterinary / medical evidence (guideline or study) — PMID 36504872","verification_file":"pdf-raw/evidence/europepmc_feline_cognitive_dysfunction_diet_2026-07-22.txt"},"source_document":"Veterinary / medical evidence (guideline or study) — PMID 36504872","source_file":"pdf-raw/evidence/europepmc_feline_cognitive_dysfunction_diet_2026-07-22.txt","trust":{"authority_tier":"T2","fidelity":"paraphrase","license":"mixed","display_grade":"B"},"tokens_estimated":663,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}