{"topic_id":"evidence_exotic_leopard_gecko_metabolic_bone_disease","category":"evidence","context":"---\ntopic_id: evidence_exotic_leopard_gecko_metabolic_bone_disease\ncategory: evidence\ntitle: \"Evidence cluster — Eublepharis macularius metabolic bone disease (peer-reviewed, Europe PMC)\"\nlang: en\nsource: \"Europe PMC (Europe PubMed Central) REST search, first-hand peer-reviewed abstracts, pulled 2026-08-01\"\nsource_file: pdf-raw/evidence/europepmc_leopard_gecko_metabolic_bone_disease_2026-08-01.txt\ndate_parsed: 2026-08-01\ntokens_estimated: 4400\nverification:\n method: substring_match\n claims: 8\n passed: 8\n date: 2026-08-01\nsource_document: \"Peer-reviewed Eublepharis macularius metabolic bone disease literature (Europe PMC, first-hand abstracts)\"\ncitation:\n authority: \"Europe PMC\"\n title: \"Evidence cluster — Eublepharis macularius metabolic bone disease (peer-reviewed, Europe PMC)\"\n url: \"https://www.ebi.ac.uk/europepmc/\"\n retrieved: \"2026-08-01\"\n doc_type: \"first-hand abstracts (Europe PMC REST)\"\n needs_review: false\n---\n\n# Evidence: Eublepharis macularius metabolic bone disease\n\nSource: Europe PMC (Europe PubMed Central) REST search — first-hand peer-reviewed abstract records, pulled 2026-08-01.\nQueries covered metabolic bone disease for Eublepharis macularius.\nThe cluster returns **8** representative studies with abstracts below. Abstract text is verbatim from source; each study is traceable by PMID.\n\n## Studies\n\n- **PMID 40987466 (2025, Journal of the American Association for Laboratory Animal Science : JAALAS)** — Iridophoroma in Leopard Geckos (Eublepharis macularius): Clinical Complications and Histopathology.. Abstract (opening): Leopard geckos (Eublepharis macularius) with lemon frost morphologies are predisposed to iridophoroma, attributed to a tumor suppressor gene mutation also associated with melanoma in humans.\n Source: https://pubmed.ncbi.nlm.nih.gov/40987466/\n- **PMID 41514721 (2025, Animals : an open access journal from MDPI)** — <i>Cryptosporidium varanii</i> Infection in Captive Leopard Gecko (<i>Eublepharis macularius</i>) and Its Association with Wasting Syndrome in Thailand.. Abstract (opening): Cryptosporidiosis is a globally important protozoan disease that causes severe gastrointestinal illness in immunocompromised humans and animals and has been associated with chronic wasting and death in reptiles.\n Source: https://pubmed.ncbi.nlm.nih.gov/41514721/\n- **PMID 41600686 (2025, Veterinary sciences)** — Biochemical and Hepatic Determinants of Reproductive Failure in Reptiles: A Review of Dystocia Pathophysiology and Management.. Abstract (opening): Dystocia represents a multifactorial and clinically significant reproductive disorder affecting a broad spectrum of reptilian species.\n Source: https://pubmed.ncbi.nlm.nih.gov/41600686/\n- **PMID 32950659 (2020, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology)** — The nocturnal leopard gecko (Eublepharis macularius) uses UVb radiation for vitamin D3 synthesis.. Abstract (opening): Vitamin D is an important regulator of calcium and phosphorus homeostasis in animals.\n Source: https://pubmed.ncbi.nlm.nih.gov/32950659/\n- **PMID 38997984 (2024, Animals : an open access journal from MDPI)** — Assessment of Animal Welfare at an Exotic Animal Fair in Poland: A Focus on the Quality of Exhibition Containers for Reptiles and Amphibians.. Abstract (opening): Given the growing number of events involving exotic animals, it is crucial to prioritize the well-being of the animals involved.\n Source: https://pubmed.ncbi.nlm.nih.gov/38997984/\n- **PMID 41150105 (2025, Veterinary sciences)** — Measuring the Rise and Fall of Plasma 25-Hydroxyvitamin D Concentrations in Blue-Tongued Skinks (<i>Tiliqua scincoides</i>) Following Ultraviolet B Exposure and Withdrawal.. Abstract (opening): Species-specific husbandry guidelines remain limited for blue-tongued skinks (Tiliqua scincoides), especially in relation to ultraviolet B (UVB) lighting and vitamin D requirements.\n Source: https://pubmed.ncbi.nlm.nih.gov/41150105/\n- **PMID 41180164 (2025, Animal welfare (South Mimms, England))** — Laying the groundwork for reptile welfare assessment in zoos and private keeping: A literature-based proposal.. Abstract (opening): With the increasing number and diversity of reptile species kept in zoological facilities and households, their welfare in captivity warrants structured and consistent evaluation.\n Source: https://pubmed.ncbi.nlm.nih.gov/41180164/\n- **PMID 32580733 (2020, Journal of ethnobiology and ethnomedicine)** — The use of fish and herptiles in traditional folk therapies in three districts of Chenab riverine area in Punjab, Pakistan.. Abstract (opening):

Background

Like botanical taxa, various species of animals are also used in traditional and modern health care systems.\n Source: https://pubmed.ncbi.nlm.nih.gov/32580733/\n\n---\n\n**Source:** `pdf-raw/evidence/europepmc_leopard_gecko_metabolic_bone_disease_2026-08-01.txt` · https://www.ebi.ac.uk/europepmc/\n","sources":["Europe PMC — Evidence cluster — Eublepharis macularius metabolic bone disease (peer-reviewed, Europe PMC) (retrieved 2026-08-01)"],"source":{"authority":"Europe PMC","title":"Evidence cluster — Eublepharis macularius metabolic bone disease (peer-reviewed, Europe PMC)","url":"https://pubmed.ncbi.nlm.nih.gov/40987466/","retrieved":"2026-08-01","ref":"PMID 40987466","doc_type":"official PDF","source_document":"Peer-reviewed Eublepharis macularius metabolic bone disease literature (Europe PMC, first-hand abstracts)","verification_file":"pdf-raw/evidence/europepmc_leopard_gecko_metabolic_bone_disease_2026-08-01.txt"},"source_document":"Peer-reviewed Eublepharis macularius metabolic bone disease literature (Europe PMC, first-hand abstracts)","source_file":"pdf-raw/evidence/europepmc_leopard_gecko_metabolic_bone_disease_2026-08-01.txt","tokens_estimated":739,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}