{"topic_id":"evidence_exotic_guinea_pig_nutrition","category":"evidence","context":"---\ntopic_id: evidence_exotic_guinea_pig_nutrition\ncategory: evidence\ntitle: \"Evidence cluster — Guinea pig (Cavia porcellus) nutrition (peer-reviewed, Europe PMC)\"\nlang: en\nsource: \"Europe PMC (Europe PubMed Central) REST search, first-hand peer-reviewed abstracts, pulled 2026-08-01\"\nsource_file: pdf-raw/evidence/europepmc_guinea_pig_nutrition_2026-08-01.txt\ndate_parsed: 2026-08-01\ntokens_estimated: 5163\nverification:\n  method: paraphrase\n  claims: 9\n  passed: 9\n  date: 2026-08-01\nsource_document: \"Peer-reviewed Guinea pig nutrition literature (Europe PMC, first-hand abstracts)\"\ncitation:\n  authority: \"Europe PMC\"\n  title: \"Evidence cluster — Guinea pig (Cavia porcellus) nutrition (peer-reviewed, Europe PMC)\"\n  url: \"https://www.ebi.ac.uk/europepmc/\"\n  retrieved: \"2026-08-01\"\n  doc_type: \"first-hand abstracts (Europe PMC REST)\"\n  needs_review: false\ncopyright_note: \"Mixed licensing per COPYRIGHT_POLICY §3: Open Access (CC BY) studies retained verbatim with attribution; non-Open-Access studies paraphrased as derived fact summaries (numbers and proper nouns preserved, sentences rewritten).\"\nlicense: mixed\nauthority_tier: T2\nauthority_tier_basis: \"T2:oa-repo\"\nauthority_tier_date: 2026-08-04\n---\n\n# Evidence: Guinea pig (Cavia porcellus) nutrition\n\nSource: Europe PMC (Europe PubMed Central) REST search — first-hand peer-reviewed abstract records, pulled 2026-08-01.\nQueries covered nutrient requirements, diet formulation, supplementation and deficiency for Cavia porcellus.\nThe cluster returns **1** representative nutrition studies with abstracts below. Abstract text is verbatim from source; each study is traceable by PMID.\n\n## Studies\n- **PMID 41630840 (2026, One health (Amsterdam, Netherlands))** — Molecular detection of zoonotic RNA viruses in guinea pigs (&lt;i&gt;Cavia porcellus&lt;/i&gt;) from small-scale family farming in the region of Cusco, Peru.. Abstract (opening): Emerging zoonotic diseases are frequently associated with close human-animal interactions in small-scale farming systems. Guinea pigs (<i>Cavia porcellus</i>) are widely raised for food in the Andean region, often under poor sanitary conditions; however, little is known about their role as reservoirs of enteric viruses with zoonotic potential. This study aimed to detect zoonotic RNA viruses in intestinal samples from guinea pigs raised on small-scale family farms in the Cusco region of Peru. A total of 34 intestinal tissue samples from adult guinea pigs showing gastrointestinal lesions were analyzed by reverse transcription polymerase chain reaction (RT-PCR) and nested PCR for the molecular detection of Coronavirus (CoV), Rotavirus A (RVA), <i>Mammalian orthoreovirus</i> (MRV), and Kobuvirus (KoV). Positive amplicons were sequenced and analyzed phylogenetically to confirm the PCR assays. Overall, 91.18% (31/34) of samples tested positive for at least one virus. RVA was the most frequently detected (58.82%), followed by CoV (29.41%), MRV (23.53%), and KoV (23.53%). Single-virus infections accounted for 20 cases and co-infections were identified in 11 cases. RVA was the most frequently detected, both in single (<i>n</i> = 9) and co-infections (<i>n</i> = 11). KoV detection was predominantly associated with co-infections rather than single infections. These findings provide the first molecular evidence of multiple zoonotic RNA viruses in guinea pigs from small-scale farming in Peru, highlighting their potential role as reservoirs in zoonotic transmission cycles. Enhanced surveillance and improved farm-level biosecurity are essential to mitigate risks of viral emergence in these traditional farming systems. *[CC BY — Open Access, verbatim with attribution.]*\n  Source: https://pubmed.ncbi.nlm.nih.gov/41630840/\n\nSource text: `pdf-raw/evidence/europepmc_guinea_pig_nutrition_2026-08-01.txt` (Europe PMC first-hand abstracts, pulled 2026-08-01).\n\n## License & attribution\n\nMixed licensing per COPYRIGHT_POLICY §3: Open Access (CC BY / CC BY-NC /\nCC BY-NC-ND) studies are reproduced verbatim with attribution under their specific\nCC license; non-Open-Access studies are paraphrased as derived fact summaries\n(numbers and proper nouns preserved, sentences rewritten). Original records:\n- https://pubmed.ncbi.nlm.nih.gov/41681373/\n- https://pubmed.ncbi.nlm.nih.gov/42375277/\n- https://pubmed.ncbi.nlm.nih.gov/42104686/\n- https://pubmed.ncbi.nlm.nih.gov/41600618/\n- https://pubmed.ncbi.nlm.nih.gov/42188743/\n- https://pubmed.ncbi.nlm.nih.gov/41787509/\n- https://pubmed.ncbi.nlm.nih.gov/42076742/\n- https://pubmed.ncbi.nlm.nih.gov/41630840/\n- https://pubmed.ncbi.nlm.nih.gov/40392031/\n\n## Cleaning removal log (2026-08-05, codebuddy)\nPMID 42075084 — rule1: Selenium in human preterm infants; not guinea pig\nPMID 41976430 — rule1: human meat processing/preservation/quality review; not guinea pig\nPMID 41002394 — rule2: prenatal choline in MOUSE model of alcohol exposure; different species\nPMID 41681373 — production feeding trial (Fe-Zn biofortified alfalfa, growth performance), not pet nutrition (removed 2026-08-24, kimi)\nPMID 42375277 — production feeding trial (45 weaned guinea pigs), not pet nutrition (removed 2026-08-24, kimi)\nPMID 42104686 — lab metabolic-disease model (maternal dyslipidaemia), not pet nutrition (removed 2026-08-24, kimi)\nPMID 41600618 — lab sensitization assay, not pet nutrition (removed 2026-08-24, kimi)\nPMID 42188743 — livestock vaccine immunogenicity (lumpy skin disease), not pet nutrition (removed 2026-08-24, kimi)\nPMID 41787509 — lab ocular-growth model (high-fat diet), not pet nutrition (removed 2026-08-24, kimi)\nPMID 42076742 — mis-clustered duplicate — kept in evidence_exotic_guinea_pig_clinical (removed 2026-08-24, kimi)\nPMID 40392031 — lab pain-electrophysiology model, not pet nutrition (removed 2026-08-24, kimi)\n","sources":["Europe PMC — Evidence cluster — Guinea pig (Cavia porcellus) nutrition (peer-reviewed, Europe PMC) (retrieved 2026-08-01)"],"source":{"authority":"Europe PMC","title":"Evidence cluster — Guinea pig (Cavia porcellus) nutrition (peer-reviewed, Europe PMC)","url":"https://pubmed.ncbi.nlm.nih.gov/41630840/","retrieved":"2026-08-01","ref":"PMID 41630840","doc_type":"official PDF","source_document":"Peer-reviewed Guinea pig nutrition literature (Europe PMC, first-hand abstracts)","verification_file":"pdf-raw/evidence/europepmc_guinea_pig_nutrition_2026-08-01.txt"},"source_document":"Peer-reviewed Guinea pig nutrition literature (Europe PMC, first-hand abstracts)","source_file":"pdf-raw/evidence/europepmc_guinea_pig_nutrition_2026-08-01.txt","trust":{"authority_tier":"T2","fidelity":"paraphrase","license":"mixed","display_grade":"B"},"tokens_estimated":904,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}