{"topic_id":"evidence_exotic_ferret_nutrition","category":"evidence","context":"---\ntopic_id: evidence_exotic_ferret_nutrition\ncategory: evidence\ntitle: \"Evidence cluster — Ferret (Mustela putorius furo) nutrition (peer-reviewed, Europe PMC)\"\nlang: en\nsource: \"Europe PMC (Europe PubMed Central) REST search, first-hand peer-reviewed abstracts, pulled 2026-08-01\"\nsource_file: pdf-raw/evidence/europepmc_ferret_nutrition_2026-08-01.txt\ndate_parsed: 2026-08-01\ntokens_estimated: 5423\nverification:\n  method: paraphrase\n  method: paraphrase\n  claims: 3\n  passed: 3\n  date: 2026-08-01\nsource_document: \"Peer-reviewed Ferret nutrition literature (Europe PMC, first-hand abstracts)\"\ncitation:\n  authority: \"Europe PMC\"\n  title: \"Evidence cluster — Ferret (Mustela putorius furo) nutrition (peer-reviewed, Europe PMC)\"\n  url: \"https://www.ebi.ac.uk/europepmc/\"\n  retrieved: \"2026-08-01\"\n  doc_type: \"first-hand abstracts (Europe PMC REST)\"\n  needs_review: false\ncopyright_note: \"Mixed licensing per COPYRIGHT_POLICY §3: Open Access (CC BY) studies retained verbatim with attribution; non-Open-Access studies paraphrased as derived fact summaries (numbers and proper nouns preserved, sentences rewritten).\"\nlicense: mixed\nauthority_tier: T2\nauthority_tier_basis: \"T2:oa-repo\"\nauthority_tier_date: 2026-08-04\n---\n\n# Evidence: Ferret (Mustela putorius furo) nutrition\n\nSource: Europe PMC (Europe PubMed Central) REST search — first-hand peer-reviewed abstract records, pulled 2026-08-01.\nQueries covered nutrient requirements, diet formulation, supplementation and deficiency for Mustela putorius furo.\nThe cluster returns **2** representative nutrition studies with abstracts below. Abstract text is verbatim from source; each study is traceable by PMID.\n\n## Studies\n- **PMID 42036348 (2026, The Journal of veterinary medical science)** — Lobular dissecting hepatitis-like chronic hepatitis with bacterial chronic cholangitis in a ferret (Mustela putorius furo).. Abstract (opening): A 1-year-3-month-old neutered female ferret presented with anorexia, weight loss, and increased liver enzymes and total bile acids. On day 49 of illness, neurologic signs appeared, necessitating humane euthanasia. Macroscopically, the liver was pale yellow with an irregular surface, and two tortuous shunt vessels from the cranial mesenteric vein to the caudal vena cava were observed cranial to the left kidney. Microscopically, single or a few hepatocytes were demarcated by reticular and collagen fibers with an extensive ductular reaction throughout all liver lobes. Bacterial chronic cholangitis was observed. Bilaterally symmetrical spongy degeneration was observed in the brain nuclei. Collectively, the present case showed lobular dissecting hepatitis-like chronic hepatitis with chronic cholangitis, accompanied by an acquired portosystemic shunt and hepatic encephalopathy. *[CC BY — Open Access, verbatim with attribution.]*\n  Source: https://pubmed.ncbi.nlm.nih.gov/42036348/\n- **PMID 42121807 (2026, Animals : an open access journal from MDPI)** — Reference Interval Determination for Digital Rectal Temperature in Healthy Ferrets (&lt;i&gt;Mustela putorius furo&lt;/i&gt;).. Abstract (opening): While digital rectal thermometry is commonly used for assessing health and identifying illness in ferrets, there is little evidence to support frequently cited ranges of normal rectal temperature in this species. The objective of this study was to establish a reference interval for digital rectal temperature in healthy ferrets (<i>Mustela putorius furo</i>). Rectal temperatures were measured using digital rectal thermometry in 56 healthy ferrets greater than four months of age. The reference interval was established using robust methods for reference interval determination, in adherence with the recommendations of the American Society for Veterinary Clinical Pathology and the Clinical and Laboratory Standards Institute. The reference interval for digital rectal temperature of healthy ferrets greater than four months of age was determined to range from 38.1 °C (confidence interval [CI] = 37.9 to 38.3 °C; 100.6 °F [CI = 100.3 to 100.9 °F]) at the lower limit to 39.9 °C (CI = 39.8 to 40.1 °C; 103.9 °F [CI = 103.6 to 104.2 °F]) at the upper limit. This reference interval for digital rectal temperature (38.1-39.9 °C [100.6-103.9 °F]) will be valuable to clinicians both performing routine health assessments and treating clinically ill ferrets. *[CC BY — Open Access, verbatim with attribution.]*\n  Source: https://pubmed.ncbi.nlm.nih.gov/42121807/\n\nSource text: `pdf-raw/evidence/europepmc_ferret_nutrition_2026-08-01.txt` (Europe PMC first-hand abstracts, pulled 2026-08-01).\n\n## License & attribution\n\nMixed licensing per COPYRIGHT_POLICY §3: Open Access (CC BY / CC BY-NC /\nCC BY-NC-ND) studies are reproduced verbatim with attribution under their specific\nCC license; non-Open-Access studies are paraphrased as derived fact summaries\n(numbers and proper nouns preserved, sentences rewritten). Original records:\n- https://pubmed.ncbi.nlm.nih.gov/42036348/\n- https://pubmed.ncbi.nlm.nih.gov/41416836/\n- https://pubmed.ncbi.nlm.nih.gov/42121807/\n\n## Cleaning removal log (2026-08-05, codebuddy)\nPMID 42159147 — AATD AAV gene therapy, ferrets as MODEL (mouse+ferret), not pet subject\nPMID 42199962 — ferrets as MODEL for VPA/LPS neurodevelopment, not pet subject\nPMID 42256162 — Bornean ferret BADGER (Melogale everetti), different species\nPMID 41987827 — probiotics in black-footed ferrets (Mustela nigripes), different species\nPMID 41698665 — ferret influenza-A housing MODEL, not pet subject\nPMID 41997988 — leopard cats & Chinese ferret-BADGERS (Melogale moschata), different species\nPMID 41926234 — ferret amygdala neuroscience MODEL, not pet subject\nPMID 42255718 — fipronil bait on cricetid mice, different species\nPMID 41598984 — ferret influenza antibody MODEL, not pet subject\nPMID 41416836 — wildlife viral surveillance (invasive mammals, New Zealand), not pet nutrition (removed 2026-08-24, kimi)\n","sources":["Europe PMC — Evidence cluster — Ferret (Mustela putorius furo) nutrition (peer-reviewed, Europe PMC) (retrieved 2026-08-01)"],"source":{"authority":"Europe PMC","title":"Evidence cluster — Ferret (Mustela putorius furo) nutrition (peer-reviewed, Europe PMC)","url":"https://pubmed.ncbi.nlm.nih.gov/42036348/","retrieved":"2026-08-01","ref":"PMID 42036348","doc_type":"official PDF","source_document":"Peer-reviewed Ferret nutrition literature (Europe PMC, first-hand abstracts)","verification_file":"pdf-raw/evidence/europepmc_ferret_nutrition_2026-08-01.txt"},"source_document":"Peer-reviewed Ferret nutrition literature (Europe PMC, first-hand abstracts)","source_file":"pdf-raw/evidence/europepmc_ferret_nutrition_2026-08-01.txt","trust":{"authority_tier":"T2","fidelity":"paraphrase","license":"mixed","display_grade":"B"},"tokens_estimated":980,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}