{"topic_id":"evidence_equine_metabolic_syndrome_diet","category":"evidence","context":"---\ntopic_id: evidence_equine_metabolic_syndrome_diet\ncategory: evidence\ntitle: \"Pet horse — equine metabolic syndrome / insulin dysregulation — diet & nutrition management (Europe PMC)\"\nlang: en\nsource: \"Europe PMC REST search (europepmc.org), query '(equine metabolic syndrome OR insulin dysregulation) AND (horse) AND (diet OR nutrition OR management)', 614 hits, pulled 2026-07-22\"\nsource_file: pdf-raw/evidence/europepmc_evidence_equine_metabolic_syndrome_diet_2026-07-22.txt\ndate_parsed: 2026-07-22\ntokens_estimated: 260\nverification:\n  method: substring_match\n  claims: 30\n  passed: 30\n  date: 2026-07-22\n---\n\n# Pet horse — equine metabolic syndrome / insulin dysregulation — diet & nutrition management (Europe PMC)\n\nSource: Europe PMC (Europe PubMed Central) REST search, query \"(equine metabolic syndrome OR insulin dysregulation) AND (horse) AND (diet OR nutrition OR management)\", 614 hits (2026-07-22). Each entry is a first-hand peer-reviewed study; the abstract opening is quoted verbatim from the publisher abstract. 6 representative studies below (filtered for species + nutrition relevance).\n\n1. PMID 42278060 — The Role of Omega-3 Fatty Acids in Horses' Nutrition-A Review. (Animals : an open access journal from MDPI, 2026). Abstract (opening): This narrative review presents examples of omega-3 fatty acids supplementation in horse nutrition. Fats are essential in equine nutrition, serving not only as an energy source but \n2. PMID 42031305 — Integrating clinical and rna-seq findings in a mare with recurrent endocrinopathic laminitis linked to equine metabolic syndrome. (Journal of equine veterinary science, 2026). Abstract (opening): Equine metabolic syndrome (EMS) is characterized by insulin dysregulation and obesity, which increase the risk of the development of hyperinsulinemia-induced laminitis (HAL). The p\n3. PMID 41825767 — Temporal variation in incretin and insulin secretion in ponies in association with dietary macronutrients. (Veterinary journal (London, England : 1997), 2026). Abstract (opening): Equine insulin dysregulation (ID) is a common condition that predisposes to hyperinsulinaemia-associated laminitis. Improved pathophysiological understanding would enable better ma\n4. PMID 42456998 — Short-Term Effects of Grazing Muzzles on Insulin in Horses with Insulin Dysregulation out at Pasture. (Journal of equine veterinary science, 2026). Abstract (opening): To mitigate insulin response and laminitis risk in insulin dysregulated (ID) horses, current management focuses on restricting pasture exposure and feeding low nonstructural carboh\n5. PMID 41302145 — Forage Carbohydrate Profiles and Endocrine Morphometric Interactions in Traditionally Managed Horses from Romania. (Life (Basel, Switzerland), 2025). Abstract (opening): Horses maintained under traditional management systems and dependent on natural forages are often exposed to seasonal and compositional variations that can affect metabolic homeost\n6. PMID 42056832 — Ertugliflozin decreases the insulin spike in non-insulin dysregulated standardbred horses following intra-articular triamcinolone administration. (Domestic animal endocrinology, 2026). Abstract (opening): Horses with equine metabolic syndrome (EMS) are at an increased risk of laminitis following corticosteroid use. Ertugliflozin reduces hyperinsulinemia in horses with EMS, and there\n\nNote: study selection and synthesis are left to the API consumer; this topic only surfaces primary sources with verbatim abstract openings.\n\nSource text: `pdf-raw/evidence/europepmc_evidence_equine_metabolic_syndrome_diet_2026-07-22.txt` (Europe PMC REST + PubMed efetch, 2026-07-22).\n","sources":[],"tokens_estimated":260,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}