{"topic_id":"evidence_canine_lyme_disease","category":"evidence","context":"---\ntopic_id: evidence_canine_lyme_disease\ncategory: evidence\ntitle: \"Evidence cluster — canine Lyme borreliosis (Borrelia burgdorferi): diagnosis, treatment & prevention (peer-reviewed, Europe PMC)\"\nlang: en\nsource: \"Europe PMC (Europe PubMed Central) REST search, first-hand peer-reviewed abstracts, pulled 2026-07-24\"\nsource_file: pdf-raw/evidence/pubmed_evidence_canine_lyme_disease_2026-07-24.txt\ndate_parsed: 2026-07-24\ntokens_estimated: 420\nverified: true\nverification:\n  method: substring_match\n  claims: 6\n  passed: 6\n  date: 2026-07-24\n---\n\n# Evidence: canine Lyme borreliosis (Borrelia burgdorferi): diagnosis, treatment & prevention (peer-reviewed, Europe PMC)\n\nSource: Europe PMC (Europe PubMed Central) REST search — first-hand peer-reviewed abstract records, pulled 2026-07-24. Query: `(\"Lyme disease\" OR \"Borrelia burgdorferi\") AND dog AND (treatment OR vaccination OR prevention OR management)`. The cluster returns **6** first-hand abstracts extracted below (verbatim sentences, each traceable by PMID).\n\n## Verified claims (verbatim, substring of saved source)\n- **PMID 41808193** — Background Both Simparica® and Simparica TRIO® chewable tablets are efficacious within 12 h against existing Ixodes scapularis infestations and within 24 h against re-infestations for 1 month.\n- **PMID 42150803** — Canine vector-borne diseases (CVBDs) pose a significant threat to dogs and public health.\n- **PMID PPR1213835** — Lyme disease, caused by Borrelia burgdorferi and transmitted by Ixodes scapularis ticks, remains a significant vector-borne illness in the United States.\n- **PMID 42115648** — Lyme disease, caused by Borrelia burgdorferi and transmitted by Ixodes scapularis ticks, remains a significant vector-borne illness in the United States.\n- **PMID 41353540** — Background Borrelia burgdorferi, the causative agent of Lyme disease, is a zoonotic vector-borne pathogen transmitted by various Ixodes tick species.\n- **PMID 42137223** — A comprehensive synthesis of current evidence on surveillance, prevention and control measures for 25 selected vector-borne diseases (VBDs) affecting animals in the EU is presented here.\n\n## Studies (PMID / year / journal / title)\n- **PMID 41808193 (2026, Parasites & vectors)** — Efficacy of Simparica and Simparica TRIO for the prevention of Borrelia burgdorferi by Ixodes scapularis.\n- **PMID 42150803 (2026, Veterinary parasitology, regional studies and reports)** — Canine vector-borne diseases in Lebanon: Unveiling prevalence trends and risk factors for public health and disease control.\n- **PMID PPR1213835 (2026, )** — A double-blinded, placebo-controlled field trial of an OspA-based oral reservoir targeted vaccine against Borrelia burgdorferi\n- **PMID 42115648 (2026, NPJ vaccines)** — A double-blinded, placebo-controlled field trial of an OspA-based oral reservoir targeted vaccine against Borrelia burgdorferi.\n- **PMID 41353540 (2025, Parasites & vectors)** — Efficacy of Credelio Quattro™ (lotilaner, moxidectin, praziquantel, and pyrantel chewable tablets) and Credelio™ (lotilaner) chewable tablets in the prevention of Borrelia burgdorferi transmission from infected Ixodes scapularis in dogs.\n- **PMID 42137223 (2026, EFSA journal. European Food Safety Authority)** — Knowledge mapping of risk mitigation measures against vector-borne diseases.\n\nSource text: `pdf-raw/evidence/pubmed_evidence_canine_lyme_disease_2026-07-24.txt` (Europe PMC first-hand abstracts, pulled 2026-07-24).\n","sources":[],"tokens_estimated":574,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}