{"topic_id":"evidence_canine_food_allergy_diet","category":"evidence","context":"---\ntopic_id: evidence_canine_food_allergy_diet\ncategory: evidence\ntitle: \"Canine food allergy / hypersensitivity — elimination diet — representative studies (Europe PMC)\"\nlang: en\nsource: \"Europe PMC REST search (europepmc.org), query 'dog food allergy elimination diet', 985 hits, pulled 2026-07-22\"\nsource_file: pdf-raw/evidence/europepmc_canine_food_allergy_diet_2026-07-22.txt\ndate_parsed: 2026-07-22\ntokens_estimated: 220\nverification:\n  method: paraphrase\n  claims: 3\n  passed: 3\n  date: 2026-07-22\nsource_document: \"Veterinary / medical evidence (guideline or study) — PMID 42245974\"\ncitation:\n  authority: \"Europe PMC\"\n  title: \"Canine food allergy / hypersensitivity — elimination diet — representative studies (Europe PMC)\"\n  url: \"https://pubmed.ncbi.nlm.nih.gov/42245974/\"\n  retrieved: \"2026-07-22\"\n  ref: \"PMID 42245974\"\n  doc_type: \"official PDF\"\n  needs_review: false\ncopyright_note: \"Mixed licensing per COPYRIGHT_POLICY §3: Open Access (CC BY) studies retained verbatim with attribution; non-Open-Access studies paraphrased as derived fact summaries (numbers and proper nouns preserved, sentences rewritten).\"\nlicense: mixed\nauthority_tier: T2\nauthority_tier_basis: \"T2:oa-repo\"\nauthority_tier_date: 2026-08-04\n---\n\n# Canine food allergy / hypersensitivity — elimination diet — representative studies (Europe PMC)\n\nSource: Europe PMC (Europe PubMed Central) REST search, query \"dog food allergy elimination diet\", 985 hits (2026-07-22). Each entry is a first-hand peer-reviewed study; the abstract opening is quoted verbatim from the publisher abstract. Six representative studies below.\n\n1. PMID 42245974 — A prospective double-blinded study evaluating threshold doses of dietary allergens that trigger adverse food reactions in dogs, and time to flare after exposure. (Frontiers in veterinary science, 2026). Abstract (opening): Introduction Adverse food reactions (AFR) are a common cause of chronic pruritus in dogs and often present as atopic dermatitis. However, the threshold dose of dietary protein *[CC BY — Open Access, verbatim with attribution.]*\n2. PMID 41391959 — *[Paraphrased derived summary — non-Open-Access source.]* Adverse food reactions (AFRs) in dogs and cats are a frequent cause of chronic pruritus and gastrointestinal disease; they encompass both immunologic (allergic) and nonimmunologic mechanisms (Vet Clin North Am Small Anim Pract, 2026). (Source excerpt truncated at abstract opening.)\n3. PMID 41346217 — Randomised, Double-Blinded, Placebo-Controlled Challenge Test With Single Food Items in Dogs With Atopic Dermatitis and Adverse Food Reactions. (Veterinary dermatology, 2026). Abstract (opening): Background Identification of offending foods in dogs with adverse food reactions is usually based on \"deterioration\" during open food challenges. Objectives To examine the placebo *[CC BY — Open Access, verbatim with attribution.]*\n\nNote: study selection and synthesis are left to the API consumer; this topic only surfaces primary sources with verbatim abstract openings.\n\nSource text: `pdf-raw/evidence/europepmc_canine_food_allergy_diet_2026-07-22.txt` (Europe PMC REST, 2026-07-22).\n\n## License & attribution\n\nMixed licensing per COPYRIGHT_POLICY §3: Open Access (CC BY / CC BY-NC /\nCC BY-NC-ND) studies are reproduced verbatim with attribution under their specific\nCC license; non-Open-Access studies are paraphrased as derived fact summaries\n(numbers and proper nouns preserved, sentences rewritten). Original records:\n- https://pubmed.ncbi.nlm.nih.gov/42245974/\n- https://pubmed.ncbi.nlm.nih.gov/41391959/\n- https://pubmed.ncbi.nlm.nih.gov/41346217/\n\n## Cleaning removal log (2026-08-05, codebuddy)\nPMID 42313883 — Human study (allergen immunotherapy for eosinophilic esophagitis, EAACI task force); target species dog absent\nPMID 41783864 — Human pediatric study (poultry meat/egg-bird syndrome allergy in children); target species dog absent\nPMID 42077678 — Human adolescent case (concurrent EoE and gastritis); target species dog absent\n","sources":["Europe PMC — Canine food allergy / hypersensitivity — elimination diet — representative studies (Europe PMC) (retrieved 2026-07-22)"],"source":{"authority":"Europe PMC","title":"Canine food allergy / hypersensitivity — elimination diet — representative studies (Europe PMC)","url":"https://pubmed.ncbi.nlm.nih.gov/42245974/","retrieved":"2026-07-22","ref":"PMID 42245974","doc_type":"official PDF","source_document":"Veterinary / medical evidence (guideline or study) — PMID 42245974","verification_file":"pdf-raw/evidence/europepmc_canine_food_allergy_diet_2026-07-22.txt"},"source_document":"Veterinary / medical evidence (guideline or study) — PMID 42245974","source_file":"pdf-raw/evidence/europepmc_canine_food_allergy_diet_2026-07-22.txt","trust":{"authority_tier":"T2","fidelity":"paraphrase","license":"mixed","display_grade":"B"},"tokens_estimated":220,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}