{"topic_id":"evidence_canine_cognitive_dysfunction_diet","category":"evidence","context":"---\ntopic_id: evidence_canine_cognitive_dysfunction_diet\ncategory: evidence\ntitle: \"Canine cognitive dysfunction — diet / antioxidants — representative studies (Europe PMC)\"\nlang: en\nsource: \"Europe PMC REST search (europepmc.org), query 'dog cognitive dysfunction diet', 1878 hits, pulled 2026-07-21\"\nsource_file: pdf-raw/evidence/europepmc_canine_cognitive_dysfunction_diet_2026-07-21.txt\ndate_parsed: 2026-07-21\ntokens_estimated: 220\nverification:\n  method: substring_match\n  claims: 30\n  passed: 30\n  date: 2026-07-21\n---\n\n# Canine cognitive dysfunction — diet / antioxidants — representative studies (Europe PMC)\n\nSource: Europe PMC (Europe PubMed Central) REST search, query \"dog cognitive dysfunction diet\", 1878 hits (2026-07-21). Each entry is a first-hand peer-reviewed study; the abstract opening is quoted verbatim from the publisher abstract. Six representative studies below.\n\n1. PMID 41976093 — Evidence-Based Clinical Management of Canine Cognitive Dysfunction Syndrome: Diagnostic Algorithms, Practical Guidelines, Critical Appraisal of Biomarkers and Translational Limitations. (Animals : an open access journal from MDPI, 2026). Abstract (opening): Canine Cognitive Dysfunction Syndrome (CCDS) is a progressive neurodegenerative disease affecting older dogs that shares many pathological mechanisms with human Alzheimer's\n2. PMID 41817417 — Diet-induced cardiac dysfunction and impaired cognitive performance in Beagles. (American journal of physiology. Regulatory, integrative and comparative physiology, 2026). Abstract (opening): Diet-induced dilated cardiomyopathy (DCM) in dogs has been linked to grain-free, pea-containing diets, possibly due to increased oligosaccharides. Since cross-sectional human\n3. PMID 41976013 — Plant-Derived Functional Ingredients in Pet Nutrition: Phytochemical Classification, Mechanisms, Efficacy, and Application in Dogs and Cats. (Animals : an open access journal from MDPI, 2026). Abstract (opening): This review classifies plant-derived functional ingredients in pet food according to phytochemical groups and application forms, including direct oral supplementation and\n4. PMID PMC12937246 — Nutrition Research in Aging Dogs and Cats: What We Know and What We Need to Do (Animals : an open access journal from MDPI, 2026). Abstract (opening): \n5. PMID 41150102 — Antioxidant Strategies for Age-Related Oxidative Damage in Dogs. (Veterinary sciences, 2025). Abstract (opening): This review examines the effects of oxidative stress on the aging process in canines, focusing on the role of antioxidants in the prevention of age-related diseases. Oxidative\n6. PMID 41860870 — OLD DOG - Validating the dog as an animal model for human aging studies. (The Journal of frailty & aging, 2026). Abstract (opening): Companion dogs represent a valuable and emerging translational model for human aging, as they share the human environment, receive comparable medical care - yet have much shorter\n\nNote: study selection and synthesis are left to the API consumer; this topic only surfaces primary sources with verbatim abstract openings.\n\nSource text: `pdf-raw/evidence/europepmc_canine_cognitive_dysfunction_diet_2026-07-21.txt` (Europe PMC REST, 2026-07-21).\n","sources":[],"tokens_estimated":220,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}