{"topic_id":"evidence_canine_cachexia_cancer_diet","category":"evidence","context":"---\ntopic_id: evidence_canine_cachexia_cancer_diet\ncategory: evidence\ntitle: \"Evidence cluster — nutritional support for cancer cachexia in dogs (peer-reviewed, Europe PMC)\"\nlang: en\nsource: \"Europe PMC (Europe PubMed Central) REST search, first-hand peer-reviewed abstracts, pulled 2026-07-27\"\nsource_file: pdf-raw/evidence/europepmc_evidence_canine_cachexia_cancer_diet_20260727.txt\ndate_parsed: 2026-07-27\ntokens_estimated: 0\nverification:\n  method: paraphrase\n  claims: 3\n  passed: 3\n  date: 2026-07-27\nsource_document: \"Veterinary / medical evidence (guideline or study) — PMID 42307841\"\ncitation:\n  authority: \"Europe PMC\"\n  title: \"Evidence cluster — nutritional support for cancer cachexia in dogs (peer-reviewed, Europe PMC)\"\n  url: \"https://pubmed.ncbi.nlm.nih.gov/42307841/\"\n  retrieved: \"2026-07-27\"\n  ref: \"PMID 42307841\"\n  doc_type: \"official abstract\"\n  needs_review: false\ncopyright_note: \"Mixed licensing per COPYRIGHT_POLICY §3: Open Access (CC BY) studies retained verbatim with attribution; non-Open-Access studies paraphrased as derived fact summaries (numbers and proper nouns preserved, sentences rewritten).\"\nlicense: mixed\nauthority_tier: T2\nauthority_tier_basis: \"T2:oa-repo\"\nauthority_tier_date: 2026-08-04\n---\n\n# Evidence: nutritional support for cancer cachexia in dogs\n\nSource: Europe PMC (Europe PubMed Central) REST search — first-hand peer-reviewed abstract records, pulled 2026-07-27. Query: `cancer cachexia dog diet`. The cluster returns **3** records in Europe PMC; 6 representative studies are extracted below. Abstract text is verbatim from source; each study is traceable by PMID.\n\n## Studies\n- **PMID 42307841 (2026, Veterinary research communications)** — Plant extracts and phytochemicals in canine and feline mammary cancer models: current evidence and comparative perspectives... Mammary tumors are among the most common neoplasms in dogs and cats, and malignant forms are clinically important in both species. Surgery remains the main treatment approach and may be combined with other treatment modalities, but advanced cases are often associated with recurrence and limited responsiveness to conventional therapies. Phytochemicals and plant extracts have rec *[CC BY — Open Access, verbatim with attribution.]*\n- **PMID 41743561 (2026, Frontiers in veterinary science)** — Differential causes of masticatory muscle disorders in dogs: a review of diagnosis, treatment and long-term management... Masticatory muscle disorders in the dog are complex and challenging cases to manage. Patients may present with inability or difficulties in opening or closing the mouth, making dysphagia and respiratory compromise major concerns. Time is of the essence in these circumstances, and prompt and accurate diagnosis and treatment are required to prevent potentially life-threatening co *[CC BY — Open Access, verbatim with attribution.]*\n- **PMID 41514729 (2025, Animals : an open access journal from MDPI)** — *[Paraphrased derived summary — non-Open-Access source.]* A systematic review and meta-analysis evaluated the scientific evidence behind three common fresh-pet-food marketing claims—that additives/preservatives/fillers harm pet health, that (excerpt cut off) human-grade or fresh processing is superior, and effects of processing on nutrition. The excerpt is cut off before the evidence synthesis; relevance to canine cancer-cachexia diet is indirect at best. (Borderline: a pet-food-claims review, not specifically cancer-cachexia nutrition.)\n\nSource text: `pdf-raw/evidence/europepmc_evidence_canine_cachexia_cancer_diet_20260727.txt` (Europe PMC first-hand abstracts, pulled 2026-07-27).\n\n## License & attribution\n\nMixed licensing per COPYRIGHT_POLICY §3: Open Access (CC BY / CC BY-NC /\nCC BY-NC-ND) studies are reproduced verbatim with attribution under their specific\nCC license; non-Open-Access studies are paraphrased as derived fact summaries\n(numbers and proper nouns preserved, sentences rewritten). Original records:\n- https://pubmed.ncbi.nlm.nih.gov/42307841/\n- https://pubmed.ncbi.nlm.nih.gov/41743561/\n- https://pubmed.ncbi.nlm.nih.gov/41514729/\n\n## Cleaning removal log (2026-08-05, codebuddy)\nPMID 42268502 — Philosophy/history-of-science paper on disease classification; no dog/canine-cachexia content (self-labeled mis-cluster).\nPMID 41953598 — Human study: nutritional intake for skin lesions in spinal-cord-injury patients (men's/women's health).\nPMID 41718388 — Lab model: organ-on-a-chip histology models; no pet dog subject.\n","sources":["Europe PMC — Evidence cluster — nutritional support for cancer cachexia in dogs (peer-reviewed, Europe PMC) (retrieved 2026-07-27)"],"source":{"authority":"Europe PMC","title":"Evidence cluster — nutritional support for cancer cachexia in dogs (peer-reviewed, Europe PMC)","url":"https://pubmed.ncbi.nlm.nih.gov/42307841/","retrieved":"2026-07-27","ref":"PMID 42307841","doc_type":"official PDF","source_document":"Veterinary / medical evidence (guideline or study) — PMID 42307841","verification_file":"pdf-raw/evidence/europepmc_evidence_canine_cachexia_cancer_diet_20260727.txt"},"source_document":"Veterinary / medical evidence (guideline or study) — PMID 42307841","source_file":"pdf-raw/evidence/europepmc_evidence_canine_cachexia_cancer_diet_20260727.txt","trust":{"authority_tier":"T2","fidelity":"paraphrase","license":"mixed","display_grade":"B"},"tokens_estimated":712,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}