{"topic_id":"companion_species_health_xanthinuria_generic_dog","category":"companion-species-health","context":"---\nlicense: permission_granted\ntopic_id: companion_species_health_xanthinuria_generic_dog\ncategory: companion-species-health\ntitle: \"Dog (Canis lupus familiaris) — Xanthinuria, generic (hereditary; OMIA-verified species predisposition)\"\nlang: en\nsource: \"OMIA (Online Mendelian Inheritance in Animals, University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-24 from local OMIA database dump.\"\nsource_file: pdf-raw/species-health/dog_xanthinuria_generic_2411.txt\ndate_parsed: 2026-08-24\ntokens_estimated: 80\nverification:\n  method: substring_match\n  claims: 3\n  passed: 3\n  date: 2026-08-24\nrecovered: false\npath: companion-species-health/companion_species_health_xanthinuria_generic_dog/01_companion_species_health_xanthinuria_generic_dog.md\nsource_document: \"OMIA — Online Mendelian Inheritance in Animals (University of Sydney)\"\ncitation:\n  authority: \"OMIA — Online Mendelian Inheritance in Animals (University of Sydney)\"\n  title: \"Dog (Canis lupus familiaris) — Xanthinuria, generic (hereditary; OMIA-verified species predisposition)\"\n  url: \"https://omia.org/OMIA001283/9615/\"\n  retrieved: \"2026-08-24\"\n  ref: \"OMIA species-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70\"\n  doc_type: \"academic animal-genetics database (species-specific disorder entries)\"\n  needs_review: false\n\nverification_derived:\n  method: derived_from_dataset\n  source: \"OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM\"\n  note: \"Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose.\"\nverification_derived:\n  method: derived_from_dataset\n  source: \"OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM\"\n  note: \"Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose.\"---\n\n# Dog (Canis lupus familiaris) — Xanthinuria, generic (hereditary; OMIA-verified species predisposition)\n\nSource: first-hand OMIA (University of Sydney) species-specific hereditary-disorder record, saved verbatim to `source_file`; every claim below is a C1 byte-substring of it.\n\n## Claims\n\n- `Species: Dog (Canis lupus familiaris)`\n- `Disorder: Xanthinuria, generic`\n- `Summary: See also Xanthinuria type I and type II specific entries.`\n## Evidence (references)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- 1997. Bilateral xanthine nephrolithiasis in a dog. J Small Anim Pract — PubMed:PMID9239633 | DOI:10.1111/j.1748-5827.1997.tb03471.x — OMIA Phene_Article / Article\n- 1996. Xanthinuria (xanthine oxidase deficiency) in two Cavalier King Charles spaniels. Veterinary Quarterly — OMIA Phene_Article / Article\n- 1997. Xanthinuria in a family of Cavalier King Charles spaniels. Vet Q — PubMed:PMID9413115 | DOI:10.1080/01652176.1997.9694766 — OMIA Phene_Article / Article\n- 1998. Xanthine urolithiasis in a dachshund. Vet Rec — PubMed:PMID9807792 | DOI:10.1136/vr.143.15.420 — OMIA Phene_Article / Article\n- 2013. Urine concentrations of xanthine, hypoxanthine and uric acid in UK Cavalier King Charles spaniels. J Small Anim Pract — PubMed:PMID23859747 | DOI:10.1111/jsap.12106 — OMIA Phene_Article / Article\n- 1969. [Xanthine urinary lithiasis and xanthinuria in a dachshund. Deficiency, probably genetic, of the xanthine oxidase system]. C R Acad Hebd Seances Acad Sci D — PubMed:PMID4982510 — OMIA Phene_Article / Article\n- 2011. Xanthine urolithiasis in a Cavalier King Charles spaniel. Vet Rec — PubMed:PMID21742684 | DOI:10.1136/vr.d3932 — OMIA Phene_Article / Article\n- 1968. Xanthine calculi in a dog. Vet Rec — PubMed:PMID5212505 | DOI:10.1136/vr.83.9.228 — OMIA Phene_Article / Article\n\n## Comparative medicine (human OMIM)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- OMIM:278300 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:603592 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n## Evidence (references)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- 1997. Bilateral xanthine nephrolithiasis in a dog. J Small Anim Pract — PubMed:PMID9239633 | DOI:10.1111/j.1748-5827.1997.tb03471.x — OMIA Phene_Article / Article\n- 1996. Xanthinuria (xanthine oxidase deficiency) in two Cavalier King Charles spaniels. Veterinary Quarterly — OMIA Phene_Article / Article\n- 1997. Xanthinuria in a family of Cavalier King Charles spaniels. Vet Q — PubMed:PMID9413115 | DOI:10.1080/01652176.1997.9694766 — OMIA Phene_Article / Article\n- 1998. Xanthine urolithiasis in a dachshund. Vet Rec — PubMed:PMID9807792 | DOI:10.1136/vr.143.15.420 — OMIA Phene_Article / Article\n- 2013. Urine concentrations of xanthine, hypoxanthine and uric acid in UK Cavalier King Charles spaniels. J Small Anim Pract — PubMed:PMID23859747 | DOI:10.1111/jsap.12106 — OMIA Phene_Article / Article\n- 1969. [Xanthine urinary lithiasis and xanthinuria in a dachshund. Deficiency, probably genetic, of the xanthine oxidase system]. C R Acad Hebd Seances Acad Sci D — PubMed:PMID4982510 — OMIA Phene_Article / Article\n- 2011. Xanthine urolithiasis in a Cavalier King Charles spaniel. Vet Rec — PubMed:PMID21742684 | DOI:10.1136/vr.d3932 — OMIA Phene_Article / Article\n- 1968. Xanthine calculi in a dog. Vet Rec — PubMed:PMID5212505 | DOI:10.1136/vr.83.9.228 — OMIA Phene_Article / Article\n\n## Comparative medicine (human OMIM)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- OMIM:278300 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:603592 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n","sources":["companion-species-health — Dog (Canis lupus familiaris) — Xanthinuria, generic (hereditary; OMIA-verified species predisposition)"],"source":{"authority":"companion-species-health","title":"Dog (Canis lupus familiaris) — Xanthinuria, generic (hereditary; OMIA-verified species predisposition)","url":"https://pubmed.ncbi.nlm.nih.gov/9239633/","retrieved":"","ref":"PMID 9239633","doc_type":"official source","source_document":"","verification_file":""},"source_document":"","source_file":"","trust":{"authority_tier":"ungraded","fidelity":"verbatim","license":null,"display_grade":"pending"},"tokens_estimated":993,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}