{"topic_id":"companion_species_health_osteopetrosis_rabbit","category":"companion-species-health","context":"---\nlicense: permission_granted\ntopic_id: companion_species_health_osteopetrosis_rabbit\ncategory: companion-species-health\ntitle: \"Rabbit (Oryctolagus cuniculus) — Osteopetrosis (hereditary; OMIA-verified species predisposition)\"\nlang: en\nsource: \"OMIA (Online Mendelian Inheritance in Animals, University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-24 from local OMIA database dump.\"\nsource_file: pdf-raw/species-health/rabbit_osteopetrosis_2019.txt\ndate_parsed: 2026-08-24\ntokens_estimated: 80\nverification:\n  method: substring_match\n  claims: 3\n  passed: 3\n  date: 2026-08-24\nrecovered: false\npath: companion-species-health/companion_species_health_osteopetrosis_rabbit/01_companion_species_health_osteopetrosis_rabbit.md\nsource_document: \"OMIA — Online Mendelian Inheritance in Animals (University of Sydney)\"\ncitation:\n  authority: \"OMIA — Online Mendelian Inheritance in Animals (University of Sydney)\"\n  title: \"Rabbit (Oryctolagus cuniculus) — Osteopetrosis (hereditary; OMIA-verified species predisposition)\"\n  url: \"https://omia.org/OMIA000755/9986/\"\n  retrieved: \"2026-08-24\"\n  ref: \"OMIA species-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70\"\n  doc_type: \"academic animal-genetics database (species-specific disorder entries)\"\n  needs_review: false\n\nverification_derived:\n  method: derived_from_dataset\n  source: \"OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM\"\n  note: \"Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose.\"---\n\n# Rabbit (Oryctolagus cuniculus) — Osteopetrosis (hereditary; OMIA-verified species predisposition)\n\nSource: first-hand OMIA (University of Sydney) species-specific hereditary-disorder record, saved verbatim to `source_file`; every claim below is a C1 byte-substring of it.\n\n## Claims\n\n- `Species: Rabbit (Oryctolagus cuniculus)`\n- `Disorder: Osteopetrosis`\n- `Summary: See Robinson (1958, pp. 348-349).`\n## Associated gene(s)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- OMIA entry symbol: os (no structured Phene_Gene link)\n\n## Evidence (references)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- 1991. Congenitally osteosclerotic (os/os) rabbits are not cured by bone marrow transplantation from normal littermates. Am J Anat — PubMed:PMID1759690 | DOI:10.1002/aja.1001920307 — OMIA Phene_Article / Article\n- 1948. Hereditary osteopetrosis of the rabbit. Fed Proc — PubMed:PMID18932635 — OMIA Phene_Article / Article\n- 1948. Hereditary osteopetrosis of the rabbit; general features and course of disease; genetic aspects. J Exp Med — PubMed:PMID18103397 | DOI:10.1084/jem.88.6.579 — OMIA Phene_Article / Article\n- 1948. Hereditary osteopetrosis of the rabbit; X-ray, hematologic, and chemical observations. J Exp Med — PubMed:PMID18103398 — OMIA Phene_Article / Article\n- 1950. Hereditary osteopetrosis of the rabbit. III. Pathologic observations; skeletal abnormalities. J Exp Med — PubMed:PMID14784539 — OMIA Phene_Article / Article\n- 1950. Hereditary osteopetrosis of the rabbit. IV. Pathologic observations; general features. J Exp Med — PubMed:PMID14784540 — OMIA Phene_Article / Article\n- 1986. The osteopetrotic rabbit: general and skeletal features of a new outbred stock. Bone — PubMed:PMID3790375 — OMIA Phene_Article / Article\n- 1987. The osteopetrotic rabbit: skeletal cytology and ultrastructure. Am J Anat — PubMed:PMID3578090 | DOI:10.1002/aja.1001780310 — OMIA Phene_Article / Article\n- 1989. Treatment of congenital osteopetrosis in the rabbit with high-dose 1,25-dihydroxyvitamin D. J Bone Miner Res — PubMed:PMID2718779 | DOI:10.1002/jbmr.5650040109 — OMIA Phene_Article / Article\n- 1990. Relationship of abnormalities in dental and skeletal development in the osteopetrotic (os) rabbit. J Oral Pathol Med — PubMed:PMID2313606 — OMIA Phene_Article / Article\n- 1990. Defective osteoclast differentiation and function in the osteopetrotic (os) rabbit. Am J Anat — PubMed:PMID2393000 | DOI:10.1002/aja.1001880412 — OMIA Phene_Article / Article\n- 1990. Effects of 1,25 dihydroxyvitamin D on osteoclast number and cytochemistry in normal and osteopetrotic (os) rabbits. Am J Anat — PubMed:PMID2148052 | DOI:10.1002/aja.1001890309 — OMIA Phene_Article / Article\n- (1 additional references in OMIA)\n\n## Comparative medicine (human OMIM)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- OMIM:259700 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:259710 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:259720 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:259730 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:600329 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n","sources":["companion-species-health — Rabbit (Oryctolagus cuniculus) — Osteopetrosis (hereditary; OMIA-verified species predisposition)"],"source":{"authority":"companion-species-health","title":"Rabbit (Oryctolagus cuniculus) — Osteopetrosis (hereditary; OMIA-verified species predisposition)","url":"https://pubmed.ncbi.nlm.nih.gov/1759690/","retrieved":"","ref":"PMID 1759690","doc_type":"official source","source_document":"","verification_file":""},"source_document":"","source_file":"","trust":{"authority_tier":"ungraded","fidelity":"verbatim","license":null,"display_grade":"pending"},"tokens_estimated":826,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}