{"topic_id":"companion_species_health_knees_and_teeth_syndrome_cat","category":"companion-species-health","context":"---\nlicense: permission_granted\ntopic_id: companion_species_health_knees_and_teeth_syndrome_cat\ncategory: companion-species-health\ntitle: \"Cat (Felis catus) — knees and teeth syndrome (hereditary; OMIA-verified species predisposition)\"\nlang: en\nsource: \"OMIA (Online Mendelian Inheritance in Animals, University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-24 from local OMIA database dump.\"\nsource_file: pdf-raw/species-health/cat_knees_and_teeth_syndrome_5385.txt\ndate_parsed: 2026-08-24\ntokens_estimated: 149\nverification:\n  method: substring_match\n  claims: 3\n  passed: 3\n  date: 2026-08-24\nrecovered: false\npath: companion-species-health/companion_species_health_knees_and_teeth_syndrome_cat/01_companion_species_health_knees_and_teeth_syndrome_cat.md\nsource_document: \"OMIA — Online Mendelian Inheritance in Animals (University of Sydney)\"\ncitation:\n  authority: \"OMIA — Online Mendelian Inheritance in Animals (University of Sydney)\"\n  title: \"Cat (Felis catus) — knees and teeth syndrome (hereditary; OMIA-verified species predisposition)\"\n  url: \"https://omia.org/OMIA002711/9685/\"\n  retrieved: \"2026-08-24\"\n  ref: \"OMIA species-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70\"\n  doc_type: \"academic animal-genetics database (species-specific disorder entries)\"\n  needs_review: false\n\nverification_derived:\n  method: derived_from_dataset\n  source: \"OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM\"\n  note: \"Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose.\"---\n\n# Cat (Felis catus) — knees and teeth syndrome (hereditary; OMIA-verified species predisposition)\n\nSource: first-hand OMIA (University of Sydney) species-specific hereditary-disorder record, saved verbatim to `source_file`; every claim below is a C1 byte-substring of it.\n\n## Claims\n\n- `Species: Cat (Felis catus)`\n- `Disorder: knees and teeth syndrome`\n- `Clin feat: Bell et al. (2023): \"PADS is clinically characterized by insufficiency fractures of the patella and in many cases fractures of other bones, persistent deciduous teeth, and unerupted permanent teeth [Langley-Hobbs & Ball, 2005; Langley-Hobbs, 2009; Reyes et al., 2019; Howes et al., 2019]. Clinical and radiographic abnormalities in the skull and dentition of cats with PADS have been reported with osteomyelitis as a potential complication [Howes et al., 2019].\"`\n## Associated gene(s)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- OMIA entry symbol: PADS (no structured Phene_Gene link)\n\n## Evidence (references)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- 2019. Skull pathology in 10 cats with patellar fracture and dental anomaly syndrome. J Feline Med Surg — PubMed:PMID30196748 | DOI:10.1177/1098612X18797368 — OMIA Phene_Article / Article\n- 2005. Acute patella fractures in cats. Vet Rec — PubMed:PMID15816192 | DOI:10.1136/vr.156.12.392 — OMIA Phene_Article / Article\n- 2009. Survey of 52 fractures of the patella in 34 cats. Vet Rec — PubMed:PMID19151405 | DOI:10.1136/vr.164.3.80 — OMIA Phene_Article / Article\n- 2019. Incidence and types of preceding and subsequent fractures in cats with patellar fracture and dental anomaly syndrome. J Feline Med Surg — PubMed:PMID30345863 | DOI:10.1177/1098612X18800837 — OMIA Phene_Article / Article\n- 2023. Characterization of oral pathology in cats affected by patellar fracture and dental anomaly syndrome (PADS). J Vet Dent — PubMed:PMID37248965 | DOI:10.1177/08987564231175594 — OMIA Phene_Article / Article\n","sources":["companion-species-health — Cat (Felis catus) — knees and teeth syndrome (hereditary; OMIA-verified species predisposition)"],"source":{"authority":"companion-species-health","title":"Cat (Felis catus) — knees and teeth syndrome (hereditary; OMIA-verified species predisposition)","url":"https://pubmed.ncbi.nlm.nih.gov/30196748/","retrieved":"","ref":"PMID 30196748","doc_type":"official source","source_document":"","verification_file":""},"source_document":"","source_file":"","trust":{"authority_tier":"ungraded","fidelity":"verbatim","license":null,"display_grade":"pending"},"tokens_estimated":618,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}