{"topic_id":"companion_species_health_familial_stomatocytosis_hypertrophic_gastritis_dog","category":"companion-species-health","context":"---\nlicense: permission_granted\ntopic_id: companion_species_health_familial_stomatocytosis_hypertrophic_gastritis_dog\ncategory: companion-species-health\ntitle: \"Dog (Canis lupus familiaris) — Familial stomatocytosis hypertrophic gastritis (hereditary; OMIA-verified species predisposition)\"\nlang: en\nsource: \"OMIA (Online Mendelian Inheritance in Animals, University of Sydney) species-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-24 from local OMIA database dump.\"\nsource_file: pdf-raw/species-health/dog_familial_stomatocytosis_hypertrophic_gastritis_1977.txt\ndate_parsed: 2026-08-24\ntokens_estimated: 206\nverification:\n  method: substring_match\n  claims: 4\n  passed: 4\n  date: 2026-08-24\nrecovered: false\npath: companion-species-health/companion_species_health_familial_stomatocytosis_hypertrophic_gastritis_dog/01_companion_species_health_familial_stomatocytosis_hypertrophic_gastritis_dog.md\nsource_document: \"OMIA — Online Mendelian Inheritance in Animals (University of Sydney)\"\ncitation:\n  authority: \"OMIA — Online Mendelian Inheritance in Animals (University of Sydney)\"\n  title: \"Dog (Canis lupus familiaris) — Familial stomatocytosis hypertrophic gastritis (hereditary; OMIA-verified species predisposition)\"\n  url: \"https://omia.org/OMIA001178/9615/\"\n  retrieved: \"2026-08-24\"\n  ref: \"OMIA species-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70\"\n  doc_type: \"academic animal-genetics database (species-specific disorder entries)\"\n  needs_review: false\n\nverification_derived:\n  method: derived_from_dataset\n  source: \"OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM\"\n  note: \"Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose.\"\nverification_derived:\n  method: derived_from_dataset\n  source: \"OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM\"\n  note: \"Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose.\"---\n\n# Dog (Canis lupus familiaris) — Familial stomatocytosis hypertrophic gastritis (hereditary; OMIA-verified species predisposition)\n\nSource: first-hand OMIA (University of Sydney) species-specific hereditary-disorder record, saved verbatim to `source_file`; every claim below is a C1 byte-substring of it.\n\n## Claims\n\n- `Species: Dog (Canis lupus familiaris)`\n- `Disorder: Familial stomatocytosis hypertrophic gastritis`\n- `Clin feat: Slappendel et al. (1991): \"The main clinical problems were diarrhoea, icterus, and ataxia and paresis of the pelvic limbs. Laboratory evaluation revealed abnormal red cell shape (stomatocytosis), increased osmotic fragility, haemolytic anaemia, and increased liver enzymes and serum bilirubin. Gastroscopic and histopathologic examination of the gastric mucosa revealed hypertrophic gastritis resembling Ménétrier's disease in man. ... Electroneurography in 2 dogs revealed polyneuropathy.\"`\n- `Pathology: Slappendel et al. (1991): \"Histologic findings in the liver were suggestive of progressive liver disease. Cysts were found in the kidneys of the five oldest patients.\"`\n## Evidence (references)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- 1991. Familial stomatocytosis--hypertrophic gastritis (FSHG), a newly recognised disease in the dog (Drentse patrijshond). Vet Q — PubMed:PMID2021052 | DOI:10.1080/01652176.1991.9694282 — OMIA Phene_Article / Article\n- 1994. Normal cations and abnormal membrane lipids in the red blood cells of dogs with familial stomatocytosis-hypertrophic gastritis. Blood — PubMed:PMID8043871 — OMIA Phene_Article / Article\n\n## Comparative medicine (human OMIM)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- OMIM:185000 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:194380 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:185020 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n## Evidence (references)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- 1991. Familial stomatocytosis--hypertrophic gastritis (FSHG), a newly recognised disease in the dog (Drentse patrijshond). Vet Q — PubMed:PMID2021052 | DOI:10.1080/01652176.1991.9694282 — OMIA Phene_Article / Article\n- 1994. Normal cations and abnormal membrane lipids in the red blood cells of dogs with familial stomatocytosis-hypertrophic gastritis. Blood — PubMed:PMID8043871 — OMIA Phene_Article / Article\n\n## Comparative medicine (human OMIM)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- OMIM:185000 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:194380 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:185020 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n","sources":["companion-species-health — Dog (Canis lupus familiaris) — Familial stomatocytosis hypertrophic gastritis (hereditary; OMIA-verified species predisposition)"],"source":{"authority":"companion-species-health","title":"Dog (Canis lupus familiaris) — Familial stomatocytosis hypertrophic gastritis (hereditary; OMIA-verified species predisposition)","url":"https://pubmed.ncbi.nlm.nih.gov/2021052/","retrieved":"","ref":"PMID 2021052","doc_type":"official source","source_document":"","verification_file":""},"source_document":"","source_file":"","trust":{"authority_tier":"ungraded","fidelity":"verbatim","license":null,"display_grade":"pending"},"tokens_estimated":799,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}