{"topic_id":"companion_breed_health_toyger_omia2542_cat","category":"companion-breed-health","context":"---\nlicense: permission_granted\ntopic_id: companion_breed_health_toyger_omia2542_cat\ncategory: companion-breed-health\ntitle: \"Toyger — Hair morphology, glitter (hereditary; OMIA-verified breed predisposition)\"\nlang: en\nsource: \"OMIA (Online Mendelian Inheritance in Animals, University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-02 from local OMIA database dump.\"\nsource_file: pdf-raw/breed-health/toyger_omia2542_2542.txt\ndate_parsed: 2026-08-02\ntokens_estimated: 80\nverification:\n  method: substring_match\n  claims: 5\n  passed: 5\n  date: 2026-08-02\nrecovered: false\npath: companion-breed-health/companion_breed_health_toyger_omia2542_cat/01_companion_breed_health_toyger_omia2542_cat.md\nsource_document: \"OMIA — Online Mendelian Inheritance in Animals (University of Sydney)\"\ncitation:\n  authority: \"OMIA — Online Mendelian Inheritance in Animals (University of Sydney)\"\n  title: \"Toyger — Hair morphology, glitter (hereditary; OMIA-verified breed predisposition)\"\n  url: \"https://omia.org/OMIA001313/9685/\"\n  retrieved: \"2026-08-02\"\n  ref: \"OMIA breed-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70\"\n  doc_type: \"academic animal-genetics database (breed-specific disorder entries)\"\n  needs_review: false\n\n\n# Toyger — Hair morphology, glitter (hereditary; OMIA-verified breed predisposition)\n\nSource: first-hand OMIA (University of Sydney) breed-specific hereditary-disorder record, saved verbatim to `source_file`; every claim below is a C1 byte-substring of it.\n\n## Claims\n\n- `Breed: Toyger (Cat)`\n- `Disorder: `\n- `Mode of inheritance: Autosomal recessive`\n- `Summary: Glitter is a coat condition that softens hair texture and causes an iridescent sheen to the coat.`\n- `Defect: no`\n## Associated gene(s)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- Gene: Entrez Gene ID 398298879 (no symbol in OMIA GeneSynonym) — OMIA Phene_Gene\n- OMIA molecular-genetics note: Kaelin et al. (2024) “discovered a 585-bp cat-specific Endogenous Retroviral Long Terminal Repeat (ERV1-3_FCa-type LTR) element insertion [omia.variant:1675] that was a strong candidate … . The LTR insertion site (chrD2: 79,707,475–79,707,478, felCat9) is defined by a 4-bp flanking direct repeat that is situated 287-bp upstream of an evolutionarily conserved&nbsp;<em>Fgfr2</em> super-enhancer (Kha…\n\n## Evidence (references)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- 1999. A scanning electron microscopy study of glitter coat trait in the fur of the Bengal cat breed. Scanning — OMIA Phene_Article / Article\n- 2024. Ancestry dynamics and trait selection in a designer cat breed. Curr Biol — PubMed:PMID38531359 | DOI:10.1016/j.cub.2024.02.075 — OMIA Phene_Article / Article\n- 2016. dbSUPER: a database of super-enhancers in mouse and human genome. Nucleic Acids Res — PubMed:PMID26438538 | DOI:10.1093/nar/gkv1002 — OMIA Phene_Article / Article\nverification_derived:\n  method: derived_from_dataset\n  source: \"OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM\"\n  note: \"Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose.\"\n","sources":["companion-breed-health — Toyger — Hair morphology, glitter (hereditary; OMIA-verified breed predisposition)"],"source":{"authority":"companion-breed-health","title":"Toyger — Hair morphology, glitter (hereditary; OMIA-verified breed predisposition)","url":"https://pubmed.ncbi.nlm.nih.gov/38531359/","retrieved":"","ref":"PMID 38531359","doc_type":"official source","source_document":"","verification_file":""},"source_document":"","source_file":"","trust":{"authority_tier":"ungraded","fidelity":"verbatim","license":null,"display_grade":"pending"},"tokens_estimated":548,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}