{"topic_id":"companion_breed_health_new_zealand_white_rabbit_omia423_rabbit","category":"companion-breed-health","context":"---\nlicense: permission_granted\ntopic_id: companion_breed_health_new_zealand_white_rabbit_omia423_rabbit\ncategory: companion-breed-health\ntitle: \"New Zealand White (Rabbit) — Coat/skin colour, oculocutaneous albinism type I (OCA1), TYR-related (hereditary; OMIA-verified breed predisposition)\"\nlang: en\nsource: \"OMIA (Online Mendelian Inheritance in Animals, University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-23 from local OMIA database dump.\"\nsource_file: pdf-raw/breed-health/new_zealand_white_rabbit_omia423_423.txt\ndate_parsed: 2026-08-23\ntokens_estimated: 80\nverification:\n  method: substring_match\n  claims: 5\n  passed: 5\n  date: 2026-08-23\nrecovered: false\npath: companion-breed-health/companion_breed_health_new_zealand_white_rabbit_omia423_rabbit/01_companion_breed_health_new_zealand_white_rabbit_omia423_rabbit.md\nsource_document: \"OMIA — Online Mendelian Inheritance in Animals (University of Sydney)\"\ncitation:\n  authority: \"OMIA — Online Mendelian Inheritance in Animals (University of Sydney)\"\n  title: \"New Zealand White (Rabbit) — Coat/skin colour, oculocutaneous albinism type I (OCA1), TYR-related (hereditary; OMIA-verified breed predisposition)\"\n  url: \"https://omia.org/OMIA000202/9986/\"\n  retrieved: \"2026-08-23\"\n  ref: \"OMIA breed-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70\"\n  doc_type: \"academic animal-genetics database (breed-specific disorder entries)\"\n  needs_review: false\n\nverification_derived:\n  method: derived_from_dataset\n  source: \"OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM\"\n  note: \"Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose.\"---\n\n# New Zealand White (Rabbit) — Coat/skin colour, oculocutaneous albinism type I (OCA1), TYR-related (hereditary; OMIA-verified breed predisposition)\n\nSource: first-hand OMIA (University of Sydney) breed-specific hereditary-disorder record, saved verbatim to `source_file`; every claim below is a C1 byte-substring of it.\n\n## Claims\n\n- `Breed: New Zealand White (Rabbit)`\n- `Disorder: `\n- `Mode of inheritance: Autosomal recessive`\n- `Summary: See Robinson (1958, pp. 338-340)`\n- `Defect: yes`\n## Associated gene(s)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- Gene: Entrez Gene ID 4118478 (no symbol in OMIA GeneSynonym) — OMIA Phene_Gene\n\n## Evidence (references)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- 1987. Linkage of albino and hemoglobin beta-chain loci in the rabbit. Journal of Heredity — PubMed:PMID3584936 — OMIA Phene_Article / Article\n- 1993. Drug-Induced Retinal Toxicity in Albino Rabbits - The Effects  of Imipenem and Aztreonam. Investigative Ophthalmology & Visual Science — PubMed:PMID8225881 — OMIA Phene_Article / Article\n- 1994. Blue-Light-Induced Dysfunction of the Blood-Retinal Barrier  at the Pigment Epithelium in Albino Versus Pigmented Rabbits. Experimental Eye Research — PubMed:PMID8157099 | DOI:10.1006/exer.1994.1192 — OMIA Phene_Article / Article\n- 1995. Comparative ocular pharmacokinetics of brimonidine after a  single dose application to the eyes of albino and pigmented  rabbits. Drug Metabolism and Disposition — PubMed:PMID7587958 — OMIA Phene_Article / Article\n- 2000. Tyrosinase gene variants in different rabbit strains. Mamm Genome — PubMed:PMID10920244 | DOI:10.1007/s003350010120 — OMIA Phene_Article / Article\n- 1996. Expression of the murine wild-type tyrosinase gene in transgenic rabbits. Transgenic Res — PubMed:PMID8840523 | DOI:10.1007/BF01980205 — OMIA Phene_Article / Article\n- 1996. YAC transgenesis in farm animals: rescue of albinism in rabbits. Mol Reprod Dev — PubMed:PMID8722692 | DOI:10.1002/(SICI)1098-2795(199605)44:1<56::AID-MRD6>3.0.CO;2-S — OMIA Phene_Article / Article\n- 1964. Catechol-O-methyl transferase and monamine oxidase activity in the ocular tissue of albino rabbits. Invest Ophthalmol — PubMed:PMID14238873 — OMIA Phene_Article / Article\n- 1905. Mendelism. Macmillan and Bowes, Cambridge — OMIA Phene_Article / Article\n- 2006. A first-generation microsatellite-based integrated genetic and cytogenetic map for the European rabbit (Oryctolagus cuniculus) and localization of angora and albino. Anim Genet — PubMed:PMID16879342 | DOI:10.1111/j.1365-2052.2006.01462.x — OMIA Phene_Article / Article\n- 1958. Genetic studies of the rabbit. Bibliographia Genetica — OMIA Phene_Article / Article\n- 1973. Recombination between buphthalmos and albino loci in the rabbit. J Hered — PubMed:PMID4782848 | DOI:10.1093/oxfordjournals.jhered.a108442 — OMIA Phene_Article / Article\n- (9 additional references in OMIA)\n\n## Comparative medicine (human OMIM)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- OMIM:203100 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:606952 (type: trait) — OMIA Group_OMIM (via OMIA_ID)\n- OMIM:606933 (type: gene) — OMIA Group_OMIM (via OMIA_ID)\n","sources":["companion-breed-health — New Zealand White (Rabbit) — Coat/skin colour, oculocutaneous albinism type I (OCA1), TYR-related (hereditary; OMIA-verified breed predisposition)"],"source":{"authority":"companion-breed-health","title":"New Zealand White (Rabbit) — Coat/skin colour, oculocutaneous albinism type I (OCA1), TYR-related (hereditary; OMIA-verified breed predisposition)","url":"https://pubmed.ncbi.nlm.nih.gov/3584936/","retrieved":"","ref":"PMID 3584936","doc_type":"official source","source_document":"","verification_file":""},"source_document":"","source_file":"","trust":{"authority_tier":"ungraded","fidelity":"verbatim","license":null,"display_grade":"pending"},"tokens_estimated":847,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}