{"topic_id":"companion_breed_health_golden_retriever_cd_dog","category":"companion-breed-health","context":"---\nlicense: permission_granted\ntopic_id: companion_breed_health_golden_retriever_cd_dog\ncategory: companion-breed-health\ntitle: \"Golden Retriever — CD (hereditary; OMIA-verified breed predisposition)\"\nlang: en\nsource: \"OMIA (Online Mendelian Inheritance in Animals, University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-02 from local OMIA database dump.\"\nsource_file: pdf-raw/breed-health/golden_retriever_cd_2791.txt\ndate_parsed: 2026-08-02\ntokens_estimated: 136\nverification:\n  method: substring_match\n  claims: 5\n  passed: 5\n  date: 2026-08-02\nrecovered: false\npath: companion-breed-health/companion_breed_health_golden_retriever_cd_dog/01_companion_breed_health_golden_retriever_cd_dog.md\nsource_document: \"OMIA — Online Mendelian Inheritance in Animals (University of Sydney)\"\ncitation:\n  authority: \"OMIA — Online Mendelian Inheritance in Animals (University of Sydney)\"\n  title: \"Golden Retriever — CD (hereditary; OMIA-verified breed predisposition)\"\n  url: \"https://omia.org/OMIA001418/9615/\"\n  retrieved: \"2026-08-02\"\n  ref: \"OMIA breed-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70\"\n  doc_type: \"academic animal-genetics database (breed-specific disorder entries)\"\n  needs_review: false\n\n\n# Golden Retriever — CD (hereditary; OMIA-verified breed predisposition)\n\nSource: first-hand OMIA (University of Sydney) breed-specific hereditary-disorder record, saved verbatim to `source_file`; every claim below is a C1 byte-substring of it.\n\n## Claims\n\n- `Breed: Golden Retriever (Dog)`\n- `Disorder: CD`\n- `Mode of inheritance: Autosomal recessive`\n- `Summary: As reported by Davidson et al. (2004), The CD phenotype was determined by videofluoroscopy, and dogs were classified as affected if the upper esophageal sphincter (UES) did not open, if there were morphologic abnormalities of the UES, or if opening of the UES was delayed for or = 6 videofluoroscopic frames (0.2 seconds) after closure of the epiglottis.`\n- `Defect: yes`\n## Evidence (references)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose.\n- 2004. Inheritance of cricopharyngeal dysfunction in Golden Retrievers.. Am J Vet Res — PubMed:PMID15027684 — OMIA Phene_Article / Article\n- 2025. Surgical management of cricopharyngeal achalasia in Spaniels results in favorable outcomes, with persistence or recurrence of mild signs documented in some dogs.. J Am Vet Med Assoc — PubMed:PMID41043475 | DOI:10.2460/javma.25.06.0415 — OMIA Phene_Article / Article\n## Evidence (references)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose.\n- 2004. Inheritance of cricopharyngeal dysfunction in Golden Retrievers. Am J Vet Res — PubMed:PMID15027684 — OMIA Phene_Article / Article\n- 2025. Surgical management of cricopharyngeal achalasia in Spaniels results in favorable outcomes, with persistence or recurrence of mild signs documented in some dogs. J Am Vet Med Assoc — PubMed:PMID41043475 | DOI:10.2460/javma.25.06.0415 — OMIA Phene_Article / Article\n## Evidence (references)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- 2004. Inheritance of cricopharyngeal dysfunction in Golden Retrievers. Am J Vet Res — PubMed:PMID15027684 — OMIA Phene_Article / Article\n- 2025. Surgical management of cricopharyngeal achalasia in Spaniels results in favorable outcomes, with persistence or recurrence of mild signs documented in some dogs. J Am Vet Med Assoc — PubMed:PMID41043475 | DOI:10.2460/javma.25.06.0415 — OMIA Phene_Article / Article\nverification_derived:\n  method: derived_from_dataset\n  source: \"OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM\"\n  note: \"Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose.\"\n## Evidence (references)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- 2004. Inheritance of cricopharyngeal dysfunction in Golden Retrievers. Am J Vet Res — PubMed:PMID15027684 — OMIA Phene_Article / Article\n- 2025. Surgical management of cricopharyngeal achalasia in Spaniels results in favorable outcomes, with persistence or recurrence of mild signs documented in some dogs. J Am Vet Med Assoc — PubMed:PMID41043475 | DOI:10.2460/javma.25.06.0415 — OMIA Phene_Article / Article\nverification_derived:\n  method: derived_from_dataset\n  source: \"OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM\"\n  note: \"Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose.\"\n## Evidence (references)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- 2004. Inheritance of cricopharyngeal dysfunction in Golden Retrievers. Am J Vet Res — PubMed:PMID15027684 — OMIA Phene_Article / Article\n- 2025. Surgical management of cricopharyngeal achalasia in Spaniels results in favorable outcomes, with persistence or recurrence of mild signs documented in some dogs. J Am Vet Med Assoc — PubMed:PMID41043475 | DOI:10.2460/javma.25.06.0415 — OMIA Phene_Article / Article\nverification_derived:\n  method: derived_from_dataset\n  source: \"OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM\"\n  note: \"Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose.\"\n","sources":["companion-breed-health — Golden Retriever — CD (hereditary; OMIA-verified breed predisposition)"],"source":{"authority":"companion-breed-health","title":"Golden Retriever — CD (hereditary; OMIA-verified breed predisposition)","url":"https://pubmed.ncbi.nlm.nih.gov/15027684/","retrieved":"","ref":"PMID 15027684","doc_type":"official source","source_document":"","verification_file":""},"source_document":"","source_file":"","trust":{"authority_tier":"ungraded","fidelity":"verbatim","license":null,"display_grade":"pending"},"tokens_estimated":955,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}