{"topic_id":"companion_breed_health_dogue_de_bordeaux_omia1373_dog","category":"companion-breed-health","context":"---\nlicense: permission_granted\ntopic_id: companion_breed_health_dogue_de_bordeaux_omia1373_dog\ncategory: companion-breed-health\ntitle: \"Dogue de Bordeaux — Osteochondritis dissecans (hereditary; OMIA-verified breed predisposition)\"\nlang: en\nsource: \"OMIA (Online Mendelian Inheritance in Animals, University of Sydney) breed-specific hereditary-disorder record, saved verbatim to source_file; C1 substring-verified. Pulled 2026-08-02 from local OMIA database dump.\"\nsource_file: pdf-raw/breed-health/dogue_de_bordeaux_omia1373_1373.txt\ndate_parsed: 2026-08-02\ntokens_estimated: 268\nverification:\n  method: substring_match\n  claims: 6\n  passed: 6\n  date: 2026-08-02\nrecovered: false\npath: companion-breed-health/companion_breed_health_dogue_de_bordeaux_omia1373_dog/01_companion_breed_health_dogue_de_bordeaux_omia1373_dog.md\nsource_document: \"OMIA — Online Mendelian Inheritance in Animals (University of Sydney)\"\ncitation:\n  authority: \"OMIA — Online Mendelian Inheritance in Animals (University of Sydney)\"\n  title: \"Dogue de Bordeaux — Osteochondritis dissecans (hereditary; OMIA-verified breed predisposition)\"\n  url: \"https://omia.org/OMIA000748/9615/\"\n  retrieved: \"2026-08-02\"\n  ref: \"OMIA breed-specific hereditary-disorder records (omia.org), derived from local OMIA database dump; dataset: https://doi.org/10.25910/2AMR-PV70\"\n  doc_type: \"academic animal-genetics database (breed-specific disorder entries)\"\n  needs_review: false\n\n\n# Dogue de Bordeaux — Osteochondritis dissecans (hereditary; OMIA-verified breed predisposition)\n\nSource: first-hand OMIA (University of Sydney) breed-specific hereditary-disorder record, saved verbatim to `source_file`; every claim below is a C1 byte-substring of it.\n\n## Claims\n\n- `Breed: Dogue de Bordeaux (Dog)`\n- `Disorder: `\n- `Mode of inheritance: Multifactorial`\n- `Clin feat: Clinical features of OCD include lameness, lameness worsened during exercise, stiffness and pain in affected joints, decreased activity levels, loss of muscle mass in affected limbs, and possible crepitus (Everts et al., 2000; van der Peijl et al. 2012; Biezyński et al., 2012; Wall et al., 2014; Murphy et al., 2019; Vezzoni and Benjamino, 2021). [IT thanks DVM student Ashley Turi, who provided the basis of this contribution in April 2022]`\n- `Defect: yes`\n- `Pathology: Pathological features of OCD that can be diagnosed via X-ray include bone loss, fragmented and calcified cartilage (joint mice), ossified cartilage flaps, widening of the articular space, visible osteophytes, and possible osteoarthritis (van der Peijl et al. 2012; Biezyński et al., 2012; Wall et al., 2014; Vezzoni and Benjamino, 2021). [IT thanks DVM student Ashley Turi, who provided the basis of this contribution in April 2022]`\n## Evidence (references)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose.\n- 1991. Osteochondritis dissecans in Labradors.. Vet Rec — PubMed:PMID2031301 | DOI:10.1136/vr.128.8.192 — OMIA Phene_Article / Article\n- 1993. The diagnostic procedures and therapy for OCD of the hindlimbs.. Veterinary Medicine — OMIA Phene_Article / Article\n- 1993. OCD of the humeral head - Its diagnosis and treatment.. Veterinary Medicine — OMIA Phene_Article / Article\n- 1993. Therapeutic approaches to osteochondritis dissecans and fragmented coronoid process.. Tijdschr Diergeneeskd — PubMed:PMID8378920 — OMIA Phene_Article / Article\n- 1994. Osteochondritis dissecans of the canine tarsal joint.. Compendium on Continuing Education for the Practicing  Veterinarian — OMIA Phene_Article / Article\n- 1995. The inheritance of osteochondritis dissecans and fragmented  coronoid process of the elbow joint in Labrador retrievers. J Am Anim Hosp Assoc — PubMed:PMID7552666 | DOI:10.5326/15473317-31-4-327 — OMIA Phene_Article / Article\n- 1995. Mineralized osteochondritis dissecans cartilage flap mimicking supraspinatus tendon mineralization. Veterinary & Comparative Orthopaedics & Traumatology — OMIA Phene_Article / Article\n- 1995. A comparison of surgical and medical treatment of fragmented coronoid process and osteochondritis dissecans of the canine elbow. Veterinary & Comparative Orthopaedics & Traumatology — OMIA Phene_Article / Article\n- 1996. A histological examination about cartilage channels in the epiphyseal cartilage of young dogs and their relationship to the localisations, that are generally affected by osteochondrosis dissecans [German]. Deutsche Tierarztliche Wochenschrift — PubMed:PMID8964237 — OMIA Phene_Article / Article\n- 1997. Arthroscopic examination and treatment of osteochondritis dissecans of the femoral condyle of six dogs. Journal of the American Animal Hospital Association — PubMed:PMID9278122 — OMIA Phene_Article / Article\n- 1998. Osteochondritis dissecans of the humeral head.. Veterinary Clinics of North America - Small Animal Practice — OMIA Phene_Article / Article\n- 1999. Bone dysplasias in the Labrador retriever: A radiographic study. Journal of the American Animal Hospital Association — PubMed:PMID10416779 — OMIA Phene_Article / Article\n- (15 additional references in OMIA)\n## Evidence (references)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose.\n- 1991. Osteochondritis dissecans in Labradors. Vet Rec — PubMed:PMID2031301 | DOI:10.1136/vr.128.8.192 — OMIA Phene_Article / Article\n- 1993. The diagnostic procedures and therapy for OCD of the hindlimbs. Veterinary Medicine — OMIA Phene_Article / Article\n- 1993. OCD of the humeral head - Its diagnosis and treatment. Veterinary Medicine — OMIA Phene_Article / Article\n- 1993. Therapeutic approaches to osteochondritis dissecans and fragmented coronoid process. Tijdschr Diergeneeskd — PubMed:PMID8378920 — OMIA Phene_Article / Article\n- 1994. Osteochondritis dissecans of the canine tarsal joint. Compendium on Continuing Education for the Practicing  Veterinarian — OMIA Phene_Article / Article\n- 1995. The inheritance of osteochondritis dissecans and fragmented  coronoid process of the elbow joint in Labrador retrievers. J Am Anim Hosp Assoc — PubMed:PMID7552666 | DOI:10.5326/15473317-31-4-327 — OMIA Phene_Article / Article\n- 1995. Mineralized osteochondritis dissecans cartilage flap mimicking supraspinatus tendon mineralization. Veterinary & Comparative Orthopaedics & Traumatology — OMIA Phene_Article / Article\n- 1995. A comparison of surgical and medical treatment of fragmented coronoid process and osteochondritis dissecans of the canine elbow. Veterinary & Comparative Orthopaedics & Traumatology — OMIA Phene_Article / Article\n- 1996. A histological examination about cartilage channels in the epiphyseal cartilage of young dogs and their relationship to the localisations, that are generally affected by osteochondrosis dissecans [German]. Deutsche Tierarztliche Wochenschrift — PubMed:PMID8964237 — OMIA Phene_Article / Article\n- 1997. Arthroscopic examination and treatment of osteochondritis dissecans of the femoral condyle of six dogs. Journal of the American Animal Hospital Association — PubMed:PMID9278122 — OMIA Phene_Article / Article\n- 1998. Osteochondritis dissecans of the humeral head. Veterinary Clinics of North America - Small Animal Practice — OMIA Phene_Article / Article\n- 1999. Bone dysplasias in the Labrador retriever: A radiographic study. Journal of the American Animal Hospital Association — PubMed:PMID10416779 — OMIA Phene_Article / Article\n- (15 additional references in OMIA)\n## Evidence (references)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- 1991. Osteochondritis dissecans in Labradors. Vet Rec — PubMed:PMID2031301 | DOI:10.1136/vr.128.8.192 — OMIA Phene_Article / Article\n- 1993. The diagnostic procedures and therapy for OCD of the hindlimbs. Veterinary Medicine — OMIA Phene_Article / Article\n- 1993. OCD of the humeral head - Its diagnosis and treatment. Veterinary Medicine — OMIA Phene_Article / Article\n- 1993. Therapeutic approaches to osteochondritis dissecans and fragmented coronoid process. Tijdschr Diergeneeskd — PubMed:PMID8378920 — OMIA Phene_Article / Article\n- 1994. Osteochondritis dissecans of the canine tarsal joint. Compendium on Continuing Education for the Practicing  Veterinarian — OMIA Phene_Article / Article\n- 1995. The inheritance of osteochondritis dissecans and fragmented  coronoid process of the elbow joint in Labrador retrievers. J Am Anim Hosp Assoc — PubMed:PMID7552666 | DOI:10.5326/15473317-31-4-327 — OMIA Phene_Article / Article\n- 1995. Mineralized osteochondritis dissecans cartilage flap mimicking supraspinatus tendon mineralization. Veterinary & Comparative Orthopaedics & Traumatology — OMIA Phene_Article / Article\n- 1995. A comparison of surgical and medical treatment of fragmented coronoid process and osteochondritis dissecans of the canine elbow. Veterinary & Comparative Orthopaedics & Traumatology — OMIA Phene_Article / Article\n- 1996. A histological examination about cartilage channels in the epiphyseal cartilage of young dogs and their relationship to the localisations, that are generally affected by osteochondrosis dissecans [German]. Deutsche Tierarztliche Wochenschrift — PubMed:PMID8964237 — OMIA Phene_Article / Article\n- 1997. Arthroscopic examination and treatment of osteochondritis dissecans of the femoral condyle of six dogs. Journal of the American Animal Hospital Association — PubMed:PMID9278122 — OMIA Phene_Article / Article\n- 1998. Osteochondritis dissecans of the humeral head. Veterinary Clinics of North America - Small Animal Practice — OMIA Phene_Article / Article\n- 1999. Bone dysplasias in the Labrador retriever: A radiographic study. Journal of the American Animal Hospital Association — PubMed:PMID10416779 — OMIA Phene_Article / Article\n- (15 additional references in OMIA)\nverification_derived:\n  method: derived_from_dataset\n  source: \"OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM\"\n  note: \"Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose.\"\n## Evidence (references)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- 1991. Osteochondritis dissecans in Labradors. Vet Rec — PubMed:PMID2031301 | DOI:10.1136/vr.128.8.192 — OMIA Phene_Article / Article\n- 1993. The diagnostic procedures and therapy for OCD of the hindlimbs. Veterinary Medicine — OMIA Phene_Article / Article\n- 1993. OCD of the humeral head - Its diagnosis and treatment. Veterinary Medicine — OMIA Phene_Article / Article\n- 1993. Therapeutic approaches to osteochondritis dissecans and fragmented coronoid process. Tijdschr Diergeneeskd — PubMed:PMID8378920 — OMIA Phene_Article / Article\n- 1994. Osteochondritis dissecans of the canine tarsal joint. Compendium on Continuing Education for the Practicing  Veterinarian — OMIA Phene_Article / Article\n- 1995. The inheritance of osteochondritis dissecans and fragmented  coronoid process of the elbow joint in Labrador retrievers. J Am Anim Hosp Assoc — PubMed:PMID7552666 | DOI:10.5326/15473317-31-4-327 — OMIA Phene_Article / Article\n- 1995. Mineralized osteochondritis dissecans cartilage flap mimicking supraspinatus tendon mineralization. Veterinary & Comparative Orthopaedics & Traumatology — OMIA Phene_Article / Article\n- 1995. A comparison of surgical and medical treatment of fragmented coronoid process and osteochondritis dissecans of the canine elbow. Veterinary & Comparative Orthopaedics & Traumatology — OMIA Phene_Article / Article\n- 1996. A histological examination about cartilage channels in the epiphyseal cartilage of young dogs and their relationship to the localisations, that are generally affected by osteochondrosis dissecans [German]. Deutsche Tierarztliche Wochenschrift — PubMed:PMID8964237 — OMIA Phene_Article / Article\n- 1997. Arthroscopic examination and treatment of osteochondritis dissecans of the femoral condyle of six dogs. Journal of the American Animal Hospital Association — PubMed:PMID9278122 — OMIA Phene_Article / Article\n- 1998. Osteochondritis dissecans of the humeral head. Veterinary Clinics of North America - Small Animal Practice — OMIA Phene_Article / Article\n- 1999. Bone dysplasias in the Labrador retriever: A radiographic study. Journal of the American Animal Hospital Association — PubMed:PMID10416779 — OMIA Phene_Article / Article\n- (15 additional references in OMIA)\nverification_derived:\n  method: derived_from_dataset\n  source: \"OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM\"\n  note: \"Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose.\"\n## Evidence (references)\nDerived from OMIA database dump (omia.xml, local); structured field, not verbatim prose. First-hand values below are verbatim substrings of the topic's pdf-raw/omia/<phene_id>.txt source file.\n- 1991. Osteochondritis dissecans in Labradors. Vet Rec — PubMed:PMID2031301 | DOI:10.1136/vr.128.8.192 — OMIA Phene_Article / Article\n- 1993. The diagnostic procedures and therapy for OCD of the hindlimbs. Veterinary Medicine — OMIA Phene_Article / Article\n- 1993. OCD of the humeral head - Its diagnosis and treatment. Veterinary Medicine — OMIA Phene_Article / Article\n- 1993. Therapeutic approaches to osteochondritis dissecans and fragmented coronoid process. Tijdschr Diergeneeskd — PubMed:PMID8378920 — OMIA Phene_Article / Article\n- 1994. Osteochondritis dissecans of the canine tarsal joint. Compendium on Continuing Education for the Practicing  Veterinarian — OMIA Phene_Article / Article\n- 1995. The inheritance of osteochondritis dissecans and fragmented  coronoid process of the elbow joint in Labrador retrievers. J Am Anim Hosp Assoc — PubMed:PMID7552666 | DOI:10.5326/15473317-31-4-327 — OMIA Phene_Article / Article\n- 1995. Mineralized osteochondritis dissecans cartilage flap mimicking supraspinatus tendon mineralization. Veterinary & Comparative Orthopaedics & Traumatology — OMIA Phene_Article / Article\n- 1995. A comparison of surgical and medical treatment of fragmented coronoid process and osteochondritis dissecans of the canine elbow. Veterinary & Comparative Orthopaedics & Traumatology — OMIA Phene_Article / Article\n- 1996. A histological examination about cartilage channels in the epiphyseal cartilage of young dogs and their relationship to the localisations, that are generally affected by osteochondrosis dissecans [German]. Deutsche Tierarztliche Wochenschrift — PubMed:PMID8964237 — OMIA Phene_Article / Article\n- 1997. Arthroscopic examination and treatment of osteochondritis dissecans of the femoral condyle of six dogs. Journal of the American Animal Hospital Association — PubMed:PMID9278122 — OMIA Phene_Article / Article\n- 1998. Osteochondritis dissecans of the humeral head. Veterinary Clinics of North America - Small Animal Practice — OMIA Phene_Article / Article\n- 1999. Bone dysplasias in the Labrador retriever: A radiographic study. Journal of the American Animal Hospital Association — PubMed:PMID10416779 — OMIA Phene_Article / Article\n- (15 additional references in OMIA)\nverification_derived:\n  method: derived_from_dataset\n  source: \"OMIA database dump (omia.xml, local); fields Gene/Variant/Article/OMIM\"\n  note: \"Structured fields (gene, variant rsID/protein change, PubMed/DOI references, OMIM cross-link) extracted from OMIA dump and presented with first-hand values; not verbatim prose.\"\n","sources":["companion-breed-health — Dogue de Bordeaux — Osteochondritis dissecans (hereditary; OMIA-verified breed predisposition)"],"source":{"authority":"companion-breed-health","title":"Dogue de Bordeaux — Osteochondritis dissecans (hereditary; OMIA-verified breed predisposition)","url":"https://pubmed.ncbi.nlm.nih.gov/2031301/","retrieved":"","ref":"PMID 2031301","doc_type":"official source","source_document":"","verification_file":""},"source_document":"","source_file":"","trust":{"authority_tier":"ungraded","fidelity":"verbatim","license":null,"display_grade":"pending"},"tokens_estimated":2668,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}