{"topic_id":"ade_vincristine_adverse_events","category":"ade","context":"---\ntopic_id: ade_vincristine_adverse_events\ncategory: ade\ntitle: \"FDA ADE reports for Vincristine (active ingredient) — total reports, species & reaction breakdown\"\nlang: en\nsource: \"openFDA animalandveterinary/event.json (FDA CVM adverse event reports), pulled 2026-07-22\"\nsource_file: pdf-raw/ade/ade_active_ingredients_2026-07-22_b24.json\ndate_parsed: 2026-07-22\ntokens_estimated: 328\nverification:\n  method: substring_match\n  claims: 26\n  passed: 26\n  date: 2026-07-22\n---\n\n# Vincristine — FDA Animal & Veterinary Adverse Event (ADE) Reports\n\nSource: openFDA `animalandveterinary/event.json`, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Vincristine is a active ingredient.\n\n## Total reports\nVincristine: 57\n\n## Reports by species (top entries)\n- Dog 52\n- Cat 5\n\n## Top reported reactions (VEDDRA terms, top entries)\n- Vomiting 21\n- Thrombocytopenia 18\n- Death by euthanasia 16\n- Lethargy (see also Central nervous system depression in 'Neurological') 15\n- Leucocytosis NOS 15\n- Anorexia 12\n- Diarrhoea 12\n- Immune mediated thrombocytopenia 12\n- Anaemia NOS 11\n- Death 10\n\nSource JSON: `pdf-raw/ade/ade_active_ingredients_2026-07-22_b24.json` (openFDA animalandveterinary/event.json, pulled 2026-07-22).\n","sources":[],"tokens_estimated":232,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}