{"topic_id":"ade_top_actives_horse","category":"ade","context":"---\ntopic_id: ade_top_actives_horse\ncategory: ade\ntitle: \"FDA ADE — top reported active ingredients in Horses\"\nlang: en\nsource: \"openFDA animalandveterinary/event.json (FDA CVM adverse event reports), pulled 2026-07-22\"\nsource_file: pdf-raw/ade/ade_species_active_2026-07-22.json\ndate_parsed: 2026-07-22\ntokens_estimated: 220\nverification:\n  method: substring_match\n  claims: 16\n  passed: 16\n  date: 2026-07-22\n---\n\n# FDA ADE — Top Reported Active Ingredients in Horses\n\nSource: openFDA `animalandveterinary/event.json`, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level and not additive. This topic ranks the active ingredients most frequently named in adverse-event reports where the affected animal species is **Horse**. Active-ingredient names are verbatim from openFDA's `drug.active_ingredients.name` field (combo products appear as combined terms, e.g. \"Pyrantel Pamoate;Sarolaner\").\n\n## Total Horse adverse-event reports\nHorse: 18382\n\n## Top reported active ingredients (Horse)\n- Omeprazole 1595\n- Ivermectin, Praziquantel 1565\n- Moxidectin 1369\n- Ivermectin 1185\n- Pergolide Mesylate 1165\n- Ceftiofur Crystalline Free Acid 882\n- Pyrantel Tartrate 739\n- Ivermectin(1.55%)/Praziquantel(7.75%) Paste 632\n- Detomidine Hydrochloride 570\n- Ketamine Hydrochloride 561\n- Hyaluronate Sodium 497\n- Flunixin Meglumine 492\n- Detomidine 454\n- Polysulfated Glycosaminoglycan 415\n- Firocoxib 402\n\n\"Lack of efficacy\" terms denote product-performance reports, not adverse reactions.\n\nSource JSON: `pdf-raw/ade/ade_species_active_2026-07-22.json` (openFDA animalandveterinary/event.json, pulled 2026-07-22).\n","sources":[],"tokens_estimated":220,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}