{"topic_id":"ade_tildipirosin_adverse_events","category":"ade","context":"---\ntopic_id: ade_tildipirosin_adverse_events\ncategory: ade\ntitle: \"FDA ADE reports for Tildipirosin (active ingredient) — total reports, species & reaction breakdown\"\nlang: en\nsource: \"openFDA animalandveterinary/event.json (FDA CVM adverse event reports), pulled 2026-07-22\"\nsource_file: pdf-raw/ade/ade_active_ingredients_2026-07-22_b18.json\ndate_parsed: 2026-07-22\ntokens_estimated: 360\nverification:\n  method: substring_match\n  claims: 30\n  passed: 30\n  date: 2026-07-22\n---\n\n# Tildipirosin — FDA Animal & Veterinary Adverse Event (ADE) Reports\n\nSource: openFDA `animalandveterinary/event.json`, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Tildipirosin is a active ingredient.\n\n## Total reports\nTildipirosin: 196\n\n## Reports by species (top entries)\n- Cattle 161\n- Human 12\n- Other Deer 1\n- Pig 1\n\n## Top reported reactions (VEDDRA terms, top entries)\n- Lack of efficacy (bacteria) - NOS 118\n- DEATH-TREATMENT FAILURE 70\n- CULTURE/TITER DATA ABNORMAL 63\n- Death 60\n- PR-LUNG(S), LESION(S) 39\n- Vials, Damaged 16\n- Containers, Abnormal 13\n- Injection site swelling 12\n- Death by euthanasia 11\n- Respiratory tract disorder NOS 10\n\nSource JSON: `pdf-raw/ade/ade_active_ingredients_2026-07-22_b18.json` (openFDA animalandveterinary/event.json, pulled 2026-07-22).\n","sources":[],"tokens_estimated":247,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}