{"topic_id":"ade_s_methoprene_adverse_events","category":"ade","context":"---\ntopic_id: ade_s_methoprene_adverse_events\ncategory: ade\ntitle: \"FDA ADE reports for (S)-Methoprene (active ingredient) — total reports, species & reaction breakdown\"\nlang: en\nsource: \"openFDA animalandveterinary/event.json (FDA CVM adverse event reports), pulled 2026-07-22\"\nsource_file: pdf-raw/ade/ade_active_ingredients_2026-07-22_b10.json\ndate_parsed: 2026-07-22\ntokens_estimated: 360\nverification:\n  method: substring_match\n  claims: 30\n  passed: 30\n  date: 2026-07-22\n---\n\n# (S)-Methoprene — FDA Animal & Veterinary Adverse Event (ADE) Reports\n\nSource: openFDA `animalandveterinary/event.json`, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. (S)-Methoprene is a active ingredient.\n\n## Total reports\n(S)-Methoprene: 1671\n\n## Reports by species (top entries)\n- Dog 1603\n- Human 27\n- Cat 11\n- Other 8\n\n## Top reported reactions (VEDDRA terms, top entries)\n- Depression 542\n- Vomiting 454\n- Ataxia 433\n- Anorexia 189\n- Trembling 150\n- Lack of efficacy (ectoparasite) - flea 130\n- Diarrhoea 128\n- Restlessness 127\n- Accidental exposure 124\n- Hyperactivity 92\n\nSource JSON: `pdf-raw/ade/ade_active_ingredients_2026-07-22_b10.json` (openFDA animalandveterinary/event.json, pulled 2026-07-22).\n","sources":[],"tokens_estimated":230,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}