{"topic_id":"ade_metronidazole_adverse_events","category":"ade","context":"---\ntopic_id: ade_metronidazole\ncategory: ade\ntitle: \"FDA ADE reports for Metronidazole — total reports, species & reaction breakdown\"\nlang: en\nsource: \"openFDA animalandveterinary/event.json (FDA CVM adverse event reports), pulled 2026-07-21\"\nsource_file: pdf-raw/ade/ade_active_ingredients_2026-07-21.json\ndate_parsed: 2026-07-21\ntokens_estimated: 200\nverification:\n  method: substring_match\n  claims: 17\n  passed: 17\n  date: 2026-07-21\n---\n\n# Metronidazole — FDA Animal & Veterinary Adverse Event (ADE) Reports\n\nSource: openFDA `animalandveterinary/event.json`, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-21. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Metronidazole is a veterinary active ingredient.\n\n## Total reports\nMetronidazole: 3583\n\n## Reports by species (top entries)\n- Dog 2980\n- Cat 386\n- Horse 10\n- Human 4\n- Ferret 2\n- Chinchilla 1\n\n## Top reported reactions (VEDDRA terms, top entries)\n- Diarrhoea 982\n- Vomiting 901\n- Lethargy (see also Central nervous system depression in 'Neurological') 563\n- Anorexia 406\n- Other abnormal test result NOS 393\n- Death by euthanasia 381\n- Elevated alanine aminotransferase (ALT) 352\n- Weight loss 316\n- Not eating 311\n- Bloody diarrhoea 295\n\n\"Lack of efficacy\" terms denote product-performance reports, not adverse reactions.\n\nSource JSON: `pdf-raw/ade/ade_active_ingredients_2026-07-21.json` (openFDA animalandveterinary/event.json, pulled 2026-07-21).\n","sources":[],"tokens_estimated":200,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}