{"topic_id":"ade_ketamine_hydrochloride_adverse_events","category":"ade","context":"---\ntopic_id: ade_ketamine_hydrochloride_adverse_events\ncategory: ade\ntitle: \"FDA ADE reports for Ketamine Hydrochloride (dissociative injectable anesthetic / analgesic) — total reports, species & reaction breakdown\"\nlang: en\nsource: \"openFDA animalandveterinary/event.json (FDA CVM adverse event reports), pulled 2026-07-22\"\nsource_file: pdf-raw/ade/ade_active_ingredients_2026-07-22_b8.json\ndate_parsed: 2026-07-22\ntokens_estimated: 193\nverification:\n  method: substring_match\n  claims: 34\n  passed: 34\n  date: 2026-07-22\n---\n\n# Ketamine Hydrochloride — FDA Animal & Veterinary Adverse Event (ADE) Reports\n\nSource: openFDA `animalandveterinary/event.json`, the FDA Center for Veterinary Medicine (CVM) adverse event report database. Data pulled 2026-07-22. Counts are report-level: one report may list multiple reactions and multiple animals, so figures are not additive and do not imply causation. Ketamine Hydrochloride is a dissociative injectable anesthetic / analgesic.\n\n## Total reports\nKetamine Hydrochloride: 4578\n\n## Reports by species (top entries)\n- Cat 2169\n- Dog 1019\n- Horse 561\n- Other 170\n- Rat 59\n- Mouse 39\n\n## Top reported reactions (VEDDRA terms, top entries)\n- INEFFECTIVE, ANESTHESIA 1277\n- Death 981\n- Cardiac arrest 333\n- Apnoea 329\n- Recovery prolonged 289\n- INEFFECTIVE, SEDATION 260\n- Convulsion 220\n- Lack of efficacy - NOS 216\n- Fever 193\n- Ataxia 164\n\n\"Lack of efficacy\" terms denote product-performance reports, not adverse reactions.\n\nSource JSON: `pdf-raw/ade/ade_active_ingredients_2026-07-22_b8.json` (openFDA animalandveterinary/event.json, pulled 2026-07-22).\n","sources":[],"tokens_estimated":266,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}