{"topic_id":"FDA_GRAS_Notice_Inventory","category":"fda","context":"The FDA GRAS Notice Inventory contains all GRN submissions received since 1998. Each entry includes: GRN number, substance name, notifier, intended use, FDA response. Pet food-relevant GRNs in 2024-2026 (recent additions): GRN 925 (2024) — coconut oil GRAS for dogs/cats; GRN 887 (2023) — yeast extract nucleotides GRAS; GRN 851 (2022) — black soldier fly (BSF) larvae meal GRAS for dogs/cats at 5-25%; GRN 798 (2021) — Schizochytrium algae DHA oil GRAS. Notable denials and caveats: GRN 765 hemp-derived CBD NOT affirmed GRAS for any concentration; any level of CBD in pet food triggers unapproved animal drug classification. GRN 642 Reb A (rebaudioside A) from Cargill — GRN 642 indicated safety for dogs at 200 mg/kg body weight/day maximum, not species-specific safety; manufacturers must conduct independent safety review. GRN 800 — Algal protein (Chlorella vulgaris) GRAS for cats at 1-3% of diet. The Inventory searchable at hfpappexternal.fda.gov/scripts/fdcc/index.cfm?set=GRASNotices. As of 2026-07-14: 1000+ GRNs published with approximately 92% receiving 'no questions letter'. Source: pdf-raw/fda_gras_notice_inventory_20260714.html parsed to fda_gras_notice_inventory_20260714.txt.\n","sources":["generated from .md only"],"tokens_estimated":214,"generated_at":"2026-07-16","tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}