{"topic_id":"EFSA_FEEDAP_vitE_tocopheryl_acetate_safety","category":"efsa","context":"---\ntopic_id: EFSA_FEEDAP_vitE_tocopheryl_acetate_safety\ncategory: efsa\ntitle: \"EFSA FEEDAP — all-rac-alpha-tocopheryl acetate (vitamin E) renewal: remains safe for all species/consumer/environment; skin-sensitisation potential open (EFSA Journal 2021;19(12))\"\nlang: en\nsource: \"EFSA FEEDAP scientific opinion, EFSA Journal 2021;19(12) (DOI 10.2903/j.efsa.2021.6974)\"\nsource_file: pdf-raw/efsa_l/vitE_feed.xml\nsource_type: journal_article\ndate_parsed: 2026-08-06\ntokens_estimated: 450\nverified: true\nverification:\n  method: paraphrase\n  claims: 3\n  passed: 3\n  date: 2026-08-06\nsource_document: \"EFSA FEEDAP — all-rac-alpha-tocopheryl acetate (vitamin E) renewal: remains safe for all species/consumer/environment; skin-sensitisation potential open (EFSA Journal 2021;19(12))\"\ncitation:\n  authority: \"EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)\"\n  title: \"EFSA FEEDAP — all-rac-alpha-tocopheryl acetate (vitamin E) renewal: remains safe for all species/consumer/environment; skin-sensitisation potential open (EFSA Journal 2021;19(12))\"\n  url: \"https://doi.org/10.2903/j.efsa.2021.6974\"\n  retrieved: \"2026-08-06\"\n  ref: \"EFSA Journal 2021;19(12)\"\n  doc_type: \"EFSA scientific opinion (Europe PMC OA full-text XML)\"\n  needs_review: false\nauthority_tier: T1\nauthority_tier_basis: \"T1:eu-body\"\nauthority_tier_date: 2026-08-06\n---\n# EFSA FEEDAP — all-rac-alpha-tocopheryl acetate (vitamin E) — renewal of authorisation\n\nSource: EFSA FEEDAP scientific opinion, EFSA Journal 2021;19(12) (DOI 10.2903/j.efsa.2021.6974), retrieved 2026-08-06 via Europe PMC OA full-text XML. Paraphrase of an EFSA opinion that the source XML tags CC-BY-ND; per project COPYRIGHT_POLICY only facts/numbers/proper-nouns are quoted verbatim, sentences rewritten.\n\n## Editorial context (read this before using the data point)\n\nThis is the **EFSA FEEDAP** jurisdiction on the nutrient/additive **all-rac-alpha-tocopheryl acetate (vitamin E)** — one of four nutrient-safety opinions in this batch (Task L). Read with the `efsa` nutrient endpoints and AAFCO/FEDIAF provisions for the same nutrient.\n\n## Key findings (paraphrase; numbers and proper nouns verbatim from source)\n\n- This is a **renewal-of-authorisation** assessment of **all-rac-alpha-tocopheryl acetate (vitamin E)**.\n- The additive **remains safe for all animal species, for consumers and for the environment** under the currently authorised conditions of use.\n- **User safety**: no concern expected from the active substance, but the Panel **cannot conclude on skin-sensitisation potential** due to lack of information; formulated-additive user safety would need specific studies.\n\n## Pet-food relevance\n\nVitamin E is an essential fat-soluble antioxidant in cat and dog diets (reproductive health, immune function, lipid stability). The unqualified 'remains safe for all animal species/consumers/environment' conclusion is the directly usable data point; the open skin-sensitisation question is the residual uncertainty.\n\n## Scope note / honest gap\n\nParaphrase of an EFSA opinion; source XML licence tag was CC-BY-ND, so this topic quotes only data points verbatim and rewrites prose. Renewal opinion (efficacy not re-assessed); full dose/characterisation statistics are not reproduced.\n","sources":["OFT3 — EFSA FEEDAP — all-rac-alpha-tocopheryl acetate (vitamin E) renewal: remains safe for all species/consumer/environment; skin-sensitisation potential open (EFSA Journal 2021;19(12)) (retrieved 2026-08-06)"],"source":{"authority":"OFT3","title":"EFSA FEEDAP — all-rac-alpha-tocopheryl acetate (vitamin E) renewal: remains safe for all species/consumer/environment; skin-sensitisation potential open (EFSA Journal 2021;19(12))","url":"https://doi.org/10.2903/j.efsa.2021.6974","retrieved":"2026-08-06","ref":"","doc_type":"official PDF","source_document":"EFSA FEEDAP — all-rac-alpha-tocopheryl acetate (vitamin E) renewal: remains safe for all species/consumer/environment; skin-sensitisation potential open (EFSA Journal 2021;19(12))","verification_file":"pdf-raw/efsa_l/vitE_feed.xml"},"source_document":"EFSA FEEDAP — all-rac-alpha-tocopheryl acetate (vitamin E) renewal: remains safe for all species/consumer/environment; skin-sensitisation potential open (EFSA Journal 2021;19(12))","source_file":"pdf-raw/efsa_l/vitE_feed.xml","trust":{"authority_tier":"T1","fidelity":"paraphrase","license":null,"display_grade":"C"},"tokens_estimated":420,"generated_at":null,"tip":"Use /api/v1/topics to discover more topics. /api/v1/nutrient for precise single-point queries. /api/v1/cross_compare for 2-3 standard comparisons."}